Article Text
Background/aims To evaluate the effect of corneal collagen crosslinking with riboflavin and UV-A as a treatment option for postlaser in situ keratomileusis keratectasia.
Methods Crosslinking was carried out in 22 eyes of 15 patients with iatrogenic keratectasia. Follow-up, according to a standardised protocol (uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), slit-lamp examination, pachymetry and topography), was performed preoperatively 1, 3, 6 and 12 months after crosslinking.
Results The mean BCVA was 0.19 (SD±0.21) logMAR preoperatively, 0.25 (SD±0.17) 1 month, 0.20 (SD±0.20) 3 months, 0.18 (SD±0.21) 6 months and 0.15 (SD±0.14) 12 months postoperatively (statistically significant postop1–postop6, p=0.0335). The maximum k-readings were 44.12 (SD±3.97) preoperatively, 46.23 (SD±4.14) 1 month, 43.88 (SD±4.25) 3 months, 45.06 (SD±5.07) 6 months and 44.43 (SD±4.06) 12 months postoperatively (statistically significant preop–postop1, p=0.0281).
Conclusion Crosslinking in patients with iatrogenic keratectasia stabilised the UCVA and BCVA as well as the maximum k-readings in our cohort. It seems to be a safe and promising procedure to stabilise the refraction and the corneal topography, and thus to stop the progression of visual loss, thereby avoiding or delaying disease progression and keratoplasty.
- Crosslinking
- keratectasia
- LASIK
- cornea
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Background/aims To evaluate the effect of corneal collagen crosslinking with riboflavin and UV-A as a treatment option for postlaser in situ keratomileusis keratectasia.
Methods Crosslinking was carried out in 22 eyes of 15 patients with iatrogenic keratectasia. Follow-up, according to a standardised protocol (uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), slit-lamp examination, pachymetry and topography), was performed preoperatively 1, 3, 6 and 12 months after crosslinking.
Results The mean BCVA was 0.19 (SD±0.21) logMAR preoperatively, 0.25 (SD±0.17) 1 month, 0.20 (SD±0.20) 3 months, 0.18 (SD±0.21) 6 months and 0.15 (SD±0.14) 12 months postoperatively (statistically significant postop1–postop6, p=0.0335). The maximum k-readings were 44.12 (SD±3.97) preoperatively, 46.23 (SD±4.14) 1 month, 43.88 (SD±4.25) 3 months, 45.06 (SD±5.07) 6 months and 44.43 (SD±4.06) 12 months postoperatively (statistically significant preop–postop1, p=0.0281).
Conclusion Crosslinking in patients with iatrogenic keratectasia stabilised the UCVA and BCVA as well as the maximum k-readings in our cohort. It seems to be a safe and promising procedure to stabilise the refraction and the corneal topography, and thus to stop the progression of visual loss, thereby avoiding or delaying disease progression and keratoplasty.
Footnotes
Competing interest None.
Patient consent Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.
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