Abstract
Twenty-four eyes with macular holes have been followed for periods ranging from one to four years. Each hole was demonstrated, clinically, to be full thickness and associated with a small, localized, retinal detachment and a posterior vitreous separation. With one exception, all eyes were within three diopters of emmetropia, and only one eye developed progression of the retinal detachment. A high incidence of systemic estrogen therapy was noted in these patients.
Zusammenfassung
24 Augen mit Maculalöchern konnten über einen Zeitraum von einem Jahr bis vier Jahren nachuntersucht werden.
Klinisch handelt es sich bei jedem Maculaloch um ein durchgreifendes Foramen mit einer kleinen, begrenzten Begleitablatio und hinterer Glaskörperabhebung.
Mit einer Ausnahme waren alle Augen praktisch emmetrop; nur in einem Auge bildete sich eine Netzhautablösung. In der untersuchten Patientengruppe war eine hohe Inzidenz von systemischer Östrogentherapie auffällig.
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References
Aaberg TM (1970) Macular holes. Survey of Ophthal 15:139
Aaberg TM, Blair CV, Gass JDM (1970) Macular holes. Am J Ophth 69:555
Alshuler JH, McLaughlin RA, Neubuerger KT (1968) Neurologic catastrophe related to oral contraceptives, Arch Neurol 19:264
Chizek DJ, Franceschetti AT (1969) Oral contraceptives: their side effects and ophthalmic manifestations. Survey Ophthalmol 14:90
Croll LJ, Croll M (1950) Hole in the macula. Amer J Ophthal 33:248
Gass JDM, Norton EWD (1969) Follow-up study of cystoid macular edema following cataract extraction. Tr Am Acad Ophth Otolaryng 73:665
Grignolo A (1942) Fibrous components of the vitreous body. Arch Ophthal 47:760
Irey NS, Norris HJ (1973) Intimal vascular lesions associated with female reproductive steroids. Arch Pathol 96:227
Kornzueig AL, Feldstein M (1950) Studies of the eye in old age. II. Holes in the macula: A clinicopathologic study. Amer J Ophthal 33:243
Margherio RR, Schepens CL (1972) Macular Break. Am J Ophth 75:219
Mikuni M, Kobayoshi S, Yaoeda H (1967) Treatment of retinal detachment with macular hole. Folia Ophthal Jap 18:659
Mori N, Yusa E (1966) Macular hole and cyst-a report of eight cases. Folia Ophthal Jap 17:628
Poltera AA (1972) The pathology of intracranial venous thrombosis in oral contraception. J Pathol 106:209
Salvatore CA (1958) Arterioles of the endometrium in the etiopathogenesis of dysfunctional hemorrhage. J Int Coll Surg 29:599
Salvatore CA (1968) Arteriole supply in normal and hyperplastic endometrium. Amer J Obstet Gynec 102:493
Somerville BW (1972) The role of estrodial withdrawal in the etiology of menstrual migraine. Neurology 22:355
Stowe GC III, Zakov ZN, Albert DM (1978) Central retinal vascular occlusion associated with oral contraceptives. Am J Ophthal 186:798
Walsh FB, Clark DB, Thompson RS, Nicholson DH (1965) Oral contraceptives and neuroophthalmologic interest. Arch Ophthal 74:628
Yaoeda H (1967) Clinical Observation on macular hole. Acta Soc Ophthal Jap 71:1723
Yoshioka H (1968) Clinical studies on macular hole. III. On the pathogenesis of the senile macular hole. Acta Soc Ophthal Jap 72:575
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This study was supported, in part, by National Institutes of Health Training Grant # 5T32EY07007, and an unrestricted grant from Research to Prevent Blindness, Inc.
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James, M., Feman, S.S. Macular Holes. Albrecht von Graefes Arch. Klin. Ophthalmol. 215, 59–63 (1980). https://doi.org/10.1007/BF00413397
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DOI: https://doi.org/10.1007/BF00413397