Abstract
The optic disc of nine patients with typical glaucomatous disc damage and ten normal controls has been studied by means of the Optic Disc Analysis program of the Topcon Image-net System. Vertical, horizontal and average cup/disc ratio (VC/D, HC/D, AC/D), disc, cup, rim area (DA, CA, RA), cup volume (CV) have been evaluated and the coefficient of variation (COV) of multiple measurements was calculated. For intra-observer intra-image variability assessment, sterovideographs of each disc were taken once and analyzed 10 times (COV range: 1.39–12.08%). Intra-observer interimage variability was evaluated on eight stereovideographs of each disc taken at one minute intervals (COV range: 1.63–96%). Inter-observer intra-image measurements were taken on each disc by 5 different observer (COV range: 1.28–27.08%).
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Quigley HT, Addicks EM, Green WR. Optic nerve damage is human glaucoma, III: Qualitative correlation of nerve fiber loss and visual field defect in glaucoma, ischemic neuropathy, papilledema and toxic neuropathy. Arch Ophthalmol 1982; 100: 135–40.
Pederson JE, Anderson DR. The mode of progressive disc cupping in ocular hypertension and glaucoma. Arch Ophthalmol 1990; 98: 490–95.
Brigatti L. Manual computer computer-aided morphometry. In: Bonomi L, Orzalesi N, eds. Glaucoma: Concepts in evolution. Amsterdam New York: Kugler 1991: 137–40.
Kruse FE, Burk ROW, Volker H-E, Zinser G, Harbarth U. Reproducibility of tomographic measurements of optic nerve head with laser tomographic scanning. Ophthalmol 1989; 96: 1320–24.
Lichter PR. Variability of expert observer in evaluating the optic disc. Trans Am Ophthalmol Soc 1976; 74: 533–72.
Varma R, Douglas GR, Steimann WC, Wijsman K, Mawson D, Spaeth GL. A comparative evaluation of three methods of analysing optic disc topography. Ophthalmic Surg 1989; 20: 813–19.
Varma R, Steimann WC, Spaeth GL, Wilson RP. Variability in digital analysis of optic disc topography. Graefe's Arch Clin Exp Ophthalmol 1988; 226: 435–42.
Caprioli J, Klingbeil U, Sears M, Pope B. Reproducibility of optic disc measurements with computerized analysis of stereoscopic video images. Arch Ophthalmol 1986; 104: 1035–39.
Mikelberg FS, Gordon GR, Schulzer M, Cornsweet TN, Wijsman K. Reliability of optic disc topographic measurements recorded with a video-ophthalmograph. Am J Ophthalmol 1984; 102: 98–102.
Rohrschneider K, Burk ROW, Volcker HE. Reproducibility of optic disc cup measurements by laser scanning tomography. Invest Ophthalmol Vis Sci 1992; 33: 883.
Iester M, Rolando M, Campagna P, Borgia L, Traverso CE, Calabria G. Valutazione della riproducibilità di analisi morfometriche papillari ottenute mediante il sistema Image-net. Atti 71° Congr. Soc. Oftalmol Italiana, Roma, 1991. Roma, 1992, 359–366.
Iester M, Rolando M, Traverso CE, Campagna P, Gandolfo E, Calabria G, Zingirian M. Observer related variability of disc measurements obtained with computerized stereovideograph-analysis. Invest Ophthalmol Vis Sci 1992; 33: 881.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Rolando, M., Iester, M., Campagna, P. et al. Measurement variability in digital analysis of optic discs. Doc Ophthalmol 85, 211–222 (1994). https://doi.org/10.1007/BF01664929
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01664929