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Topical treatment of severe corneal ulcers with cyclosporin A

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Abstract

Cyclosporin A eye drops were used on six patients to treat corneal ulcers associated with rheumatic diseases, oculomucocutaneous syndrome, and Sjögren's syndrome. Conjunctival excision was additionally carried out in two cases. All ulcers healed rapidly. The mechanism of ulcer formation involving T-lymphocytes is discussed.

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Authors and Affiliations

  1. Augenklinik der Universität, Schleichstrasse 12, D-7400, Tübingen, Federal Republic of Germany

    M. Zierhut, H. -J. Thiel, E. G. Weidle, R. Waetjen & U. Pleyer

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  1. M. Zierhut
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  2. H. -J. Thiel
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  3. E. G. Weidle
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  4. R. Waetjen
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  5. U. Pleyer
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Zierhut, M., Thiel, H.J., Weidle, E.G. et al. Topical treatment of severe corneal ulcers with cyclosporin A. Graefe's Arch Clin Exp Ophthalmol 227, 30–35 (1989). https://doi.org/10.1007/BF02169821

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  • DOI: https://doi.org/10.1007/BF02169821

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