Skip to main content
SpringerLink
Log in

Bestimmung der Lebensqualität des Patienten in der Augenheilkunde

  • Originalien
  • Published:
Der Ophthalmologe Aims and scope Submit manuscript

Zusammenfassung

Hintergrund

Eine Beurteilung der Lebensqualität von Patienten in der Augenheilkunde ist nicht nur für Studien und zur Beurteilung neuer Therapien wichtig, sondern gewinnt auch im klinischen Alltag zunehmend für therapeutische Entscheidungen an Bedeutung.

Methoden

Es steht eine Vielzahl von Instrumenten zur Messung der krankheitsübergreifenden (globalen) Lebensqualität zur Verfügung. Ein bekannter Fragebogen hierzu ist der Short Form 36 (SF 36). In der Augenheilkunde werden zur Bestimmung der auf den Sehvorgang bezogenen (visuellen) Lebensqualität spezifischere Instrumente benötigt. Wir geben einen Überblick der praktischen Bedeutung und klinischen Anwendung von Methoden zur Messung der visuellen Lebensqualität. Einige Fragebögen sind der Visual Function 14 (VF-14) oder der National Eye Institute Visual Functioning Questionnaire (NEI-VFQ). Diese werden bislang insbesondere bei häufigen ophthalmologischen Erkrankungen wie Katarakt, altersbedingter Makuladegeneration oder Glaukom eingesetzt. Wichtige Studien hierzu wurden bei einer Literaturrecherche in der Medline-Datenbank identifiziert.

Ergebnisse

Es existiert eine Reihe von Instrumenten zur Messung der visuellen Lebensqualität in der Augenheilkunde. Hohe interne Konsistenz und Validität konnten für viele dieser Instrumente nachgewiesen werden.

Schlussfolgerungen

Die Evaluierung der visuellen Lebensqualität ist ein wichtiger Parameter zur Beurteilung ophthalmologischer Erkrankungen und deren Therapie. Sie sollte von allen in Praxis und Klinik tätigen Augenärzten in alle individuellen klinischen Überlegungen mit einbezogen werden. Zudem ist sie eine bedeutsame Ergebnisvariable in klinischen und ökonomischen Studien.

Abstract

Background

The assessment of patient's quality of life is not only of vital importance for clinical trials of new therapies but also becomes more and more implemented into daily clinical therapeutical decisions.

Methods

Different methods for evaluating quality of life are available. A well-known questionnaire for measuring global quality of life is the Short Form 36 (SF 36). However, in ophthalmology more specific instruments for measuring visual quality of life are needed. We review the usefulness of specific questionnaires such as the Visual Function 14 (VF-14) or the National Eye Institute Visual Function Questionnaire (NEI-VFQ) in their application to common ophthalmologic diseases such as cataract, age-related macular degeneration and glaucoma. Studies applying these methods were identified by a search in the Medline database.

Results

Several instruments to measure visual life quality in ophthalmologic patients are available. Internal consistency and validity are shown.

Conclusions

Evaluating visual quality of life is an important parameter for assessing ophthalmologic diseases and the value of different therapies. It is an important outcome variable in clinical studies. Furthermore, individual visual quality of life should be considered in individual therapeutic decisions and helps to assess the economic effect of current and new therapies.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. Boisjoly H, Gresset J, Fontaine N et al. (1999) The VF-14 index of functional visual impairment in candidates for a corneal graft. Am J Ophthalmol 128:38–44

    Article  CAS  PubMed  Google Scholar 

  2. Broman AT, Munoz B, Rodriguez J et al. (2002) The impact of visual impairment and eye disease on vision-related quality of life in a Mexican-American population: Proyecto VER. Invest Ophthalmol Vis Sci 43:3393–3398

    PubMed  Google Scholar 

  3. Brubaker RF (1999) Decisions. Ophthalmology 1:165–168

    Google Scholar 

  4. Brüggenjürgen B (1994) Lebensqualität und volkswirtschafliche Kosten der Migräne in Deutschland. Sankt Augustin

  5. Bullinger M (1993) Indices versus profiles: advantages and disadvantages. In: Walker SR, Rosse RM (eds) Quality of life assessment. Key issues in the 1990s. MTP Press, Lancester, S 209–220

    Google Scholar 

  6. Cassard SD, Patrick DL, Damiano AM et al. (1995) Reproducibility and responsiveness of the VF-14: an index of functional impairment in patients with cataracts. Arch Ophthalmol 113:1508–1513

    CAS  PubMed  Google Scholar 

  7. Drummond MF, Stoddart GL, Torrance, GW (1987) Methods for the Economic Evaluation of Health Care Programmes Oxford [Oxfordshire]. Oxford University Press, New York

  8. Early Treatment Diabetic Retinopathy Study Research Group (1987) Treatment techniques and clinical guidelines for photocoagulation of diabetic macular edema. Early Treatment Diabetic Retinopathy Study Report Number 2. Ophthalmology 94:761–774

    PubMed  Google Scholar 

  9. Early Treatment Diabetic Retinopathy Study Research Group (1991) Early photocoagulation for diabetic retinopathy. Early Treatment Diabetic Retinopathy Study Report Number 9. Ophthalmology 98:766–785

    PubMed  Google Scholar 

  10. EuroQol Group (1990) EuroQol—A new facility for the measurement of health-related quality of life. Health Policy 16:199–208

    PubMed  Google Scholar 

  11. Gutierrez P, Wilson MR, Johnson C et al. (1997) Influence of glaucomatous visual field loss on health-related quality of life. Arch Ophthalmol 115:777–784

    CAS  PubMed  Google Scholar 

  12. Hart PM, Chakravarthy U, Stevenson MR, Jamison JQ (1999) A vision specific functional index for use in patients with age related macular degeneration. Br J Ophthalmol 83:1115–1120

    CAS  PubMed  Google Scholar 

  13. Hyman L, Schachat AP, He Q, Leske MC (2000) Hypertension, cardiovascular disease, and age-related macular degeneration. Age-Related Macular Degeneration Risk Factors Study Group. Arch Ophthalmol 118:351–358

    CAS  PubMed  Google Scholar 

  14. Johannesson M, Jönsson B, Karlsson G (1996) Outcome measurement in economic evaluation. Health Economics 5:279–296

    Google Scholar 

  15. Klein R, Rowland ML, Harris MI (1995) Racial/ethnic differences in age-related maculopathy. Third National Health and Nutrition Examination Survey. Ophthalmology 102:371–381

    CAS  PubMed  Google Scholar 

  16. Linder M, Chang TS, Scott IU et al. (1999) Validity of the Visual Function Index (VF-14) in patients with retinal disease. Arch Ophthalmol 117:1611–1616

    CAS  PubMed  Google Scholar 

  17. Mackenzie PJ, Chang TS, Scott IU et al. (2002) Assessment of vision-related function in patients with age-related macular degeneration. Ophthalmology 109:720–729

    Article  PubMed  Google Scholar 

  18. Mangione CM, Phillips RS, Seddon JM et al. (1992) Development of the activities of Daily Vision Scale: a measure of visual functional status. Med Care 30:1111–1126

    CAS  PubMed  Google Scholar 

  19. Mangione CM, Phillips RS, Lawrence MG et al. (1994) Improved visual function and attenuation of declines in health related quality of life after cataract extractation. Arch Ophthalmol 112:1419–1425

    CAS  PubMed  Google Scholar 

  20. Mangione CM, Lee PP, Berry SH et al. (1995) Development of a questionnaire for assessment of visual function: association for Research in vision and ophthalmology. Invest Ophthalmol Vis Sci 36:1962

    Google Scholar 

  21. Mangione CM, Lee PP, Berry SH et al. (1996) The NEI-VFQ 51-item test version and its relationship with visual acuity across 5 diseases: association for research in vision and ophthalmology. Invest Ophthalmol Vis Sci 37:873

    Google Scholar 

  22. Mangione CM, Berry S, Spritzer K (1998) Identifying the content area for the 51-item National Eye Institut Visual Function Questionnaire: results from focus groups with visually impaired persons. Arch Ophthalmol 116:227–233

    CAS  PubMed  Google Scholar 

  23. McClure ME, Hart PM, Jackson AJ et al. (2000) Macular degeneration: do conventional measurements of impaired visual function equate with visual disability? Br J Ophthalmol 84:244–250

    Article  CAS  PubMed  Google Scholar 

  24. Musch DC, Farjo AA, Meyer RF et al. (1997) Assessment of health-related quality of life after corneal transplantation. Am J Ophthalmol 124:1–8

    CAS  PubMed  Google Scholar 

  25. Neubauer AS, Mueller AJ, Schriever S et al. (2000) Minimally invasive therapy for clinically complete central retinal artery occlusion- results and meta-analysis of literature. Klin Monatsbl Augenheilkd 217:30–36

    Article  CAS  PubMed  Google Scholar 

  26. Parrish RK, Gedde SJ, Scott IU et al. (1997) Visual function and quality of life among patients with glaucoma. Arch Ophthalmol 115:1447–1455

    PubMed  Google Scholar 

  27. Patrick DL, Erickson P (1993) Assessing health-related quality of life for clinical decision making. In Walker SR, Rosse RM (eds) Quality of life assessment. Key issues in the 1990s. MTP Press, Lancester, S 11–63

  28. Pesudovs K, Elliott DB, Gelsthorpe SD et al. (2002) The development of the Quality of Life Impact of Refractive Correction (QIRC) Questionnaire. Poster ARVO

  29. Schöffski O (1998) Gesundheitsökonomische Evaluationen: Grundlagen und Standortbestimmung. Springer Verlag, Berlin Heidelberg New York Tokyo

  30. Scott IU, Smiddy WE, Schiffman J et al. (1999) Quality of life of low-vision patients and the impact of low-vision services. Am J Ophthalmol 128:54–62

    Article  CAS  PubMed  Google Scholar 

  31. Sharma S, Brown GC, Brown MM et al. (2001) The cost-effectiveness of photodynamic therapy for fellow eyes with subfoveal choroidal neovascularization secondary to age-related macular degeneration. Ophthalmology 110:626–627

    Google Scholar 

  32. Stadnyk K, Caldere J, Rockwood K (1998) Testing the measurement properties of the Short Form–36 in a frail elderly population. J Clin Epidemiol 51:827–835

    Article  CAS  PubMed  Google Scholar 

  33. Steinberg EP, Tielsch JM, Schein OD et al. (1994) The VF-14: an index of functional impairment in cataract patients. Arch Ophthalmol 112:630–638

    CAS  PubMed  Google Scholar 

  34. The Diabetic Retinopathy Study Research Group (1987) Indications for photocoagulation treatment of diabetic retinopathy. Diabetic Retinopathy Study Report Number 14. Int Ophthalmol Clin 27:293–353

    Google Scholar 

  35. Torrance GW (1986) Measurement of health state utilities for economic appraisal. A review. J Health Economics 5:1–30

    Google Scholar 

  36. University of Oxford, Centre for Evidence based Medicine. "Levels of evidence and Grades of Recommendations". http://www.cebm.net

  37. Ware JE, Snow KK, Kosinski M, Gandek V (1993) SF-36 Health Survey Manual and Interpretation Guide. Nimrod Press, Boston

  38. Wolffsohn JS, Cochrane AL (2000) Design of the low vision quality-of-life questionnaire (LVQOL) and measuring the outcome of low-vision rehabilitation, Am J Ophthalmol 130:793–802

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Augenklinik der Ludwig-Maximilians-Universität, München

    C. Hirneiß,  A. S. Neubauer, U. Welge-Lüßen, K. Eibl & A. Kampik

  2. Augenklinik der Ludwig-Maximilians-Universität, Mathildenstraße 8, 80336 , München

    A. S. Neubauer

Authors
  1. C. Hirneiß
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. S. Neubauer
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. U. Welge-Lüßen
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. K. Eibl
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. A. Kampik
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to A. S. Neubauer.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hirneiß, C., Neubauer, A.S., Welge-Lüßen, U. et al. Bestimmung der Lebensqualität des Patienten in der Augenheilkunde. Ophthalmologe 100, 1091–1097 (2003). https://doi.org/10.1007/s00347-003-0884-1

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00347-003-0884-1

Schlüsselwörter

Keywords

Search

Navigation