Skip to main content
SpringerLink
Log in

Chorioretinopathia centralis serosa – Netzhautfunktion und -morphologie

Mikroperimetrie und optische Kohärenztomografie im Vergleich

Central serous chorioretinopathy – retinal function and morphology

Microperimetry and optical coherence tomography

  • Originalien
  • Published:
Der Ophthalmologe Aims and scope Submit manuscript

Zusammenfassung

Hintergrund

Ziel dieser Studie war es, bei Patienten mit Chorioretinopathia centralis serosa (CCS) Netzhautfunktion und -morphologie mittels Fundusperimetrie und OCT zu vergleichen.

Patienten und Methoden

Bei 14 Augen von 14 Patienten mit einseitiger, erstmalig aufgetretener CCS wurde sowohl eine funduskontrollierte Perimetrie mit dem Microperimeter 1 (MP1) als auch eine OCT-Untersuchung durchgeführt. Analysiert wurde die Netzhautdicke ebenso wie die Lichtunterschiedsempfindlichkeit (LUE) im korrespondierenden Gesichtsfeld.

Ergebnisse

Bei allen Patienten bestand eine seröse Abhebung der zentralen neurosensorischen Retina mit einer maximalen Netzhautdicke von 381±82 μm. In der Fundusperimetrie zeigte sich ein mittlerer Defekt von 8,3±3,8 dB, der gut mit der Netzhautdicke korrelierte (r=0,73). Ebenso korrelierte die jeweils maximale Netzhautdicke gut mit der LUE im korrespondierenden Gesichtsfeldareal (r=−0,58).

Schlussfolgerungen

Das MP1 ermöglicht eine Quantifizierung funktioneller Ausfälle bei CCS. Obwohl die Sehschärfe im Durchschnitt nur geringfügig reduziert war, zeigten alle Patienten in der Mikroperimetrie ausgedehnte Skotome, die gut mit der Netzhautdicke korrelierten.

Abstract

Background

The purpose of this study was to evaluate and compare retinal function and morphology in patients with central serous chorioretinopathy (CSC) using fundus perimetry and optical coherence tomography (OCT).

Patients and methods

In 14 eyes of 14 patients with unilateral and first manifestation of CSC, fundus perimetry with the Microperimeter 1 (MP1) as well as OCT were carried out. The average retinal thickness and the average differential light threshold of the corresponding visual field were analyzed.

Results

All patients presented a serous detachment of the central neurosensory retina with a maximal retinal thickness of 381±82 μm. The microperimetric examination revealed on average a mean defect of 8.3±3.8 dB, which showed a good correlation to retinal thickness (r=0.73). Likewise, maximal retinal thickness and mean threshold values in the corresponding visual field displayed a good correlation (r=−0.58).

Conclusion

The MP1 enables quantification of functional defects in patients with CSC. Although visual acuity was only slightly reduced, all patients showed extensive scotomata in fundus perimetry, which correlated well with retinal thickness.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1
Abb. 2
Abb. 3
Abb. 4
Abb. 5
Abb. 6

Literatur

  1. Carvalho-Recchia CA, Yannuzzi LA et al. (2002) Corticosteroids and central serous chorioretinopathy. Ophthalmology 109: 1834–1837

    Article  PubMed  Google Scholar 

  2. Chauhan DS, Antcliff RJ, Rai PA et al. (2000) Papillofoveal traction in macular hole formation: the role of optical coherence tomography. Arch Ophthalmol 118: 32–38

    PubMed  Google Scholar 

  3. Goebel W, Kretzchmar-Gross T (2002) Retinal thickness in diabetic retinopathy: a study using optical coherence tomography (OCT). Retina 22: 759–767

    Article  PubMed  Google Scholar 

  4. Hee MR, Puliafito CA, Wong C et al. (1995) Optical coherence tomography of central serous chorioretinopathy. Am J Ophthalmol 120: 65–74

    PubMed  Google Scholar 

  5. Hee MR, Puliafito CA, Wong C et al. (1995) Quantitative assessment of macular edema with optical coherence tomography. Arch Ophthalmol 113: 1019–1029

    PubMed  Google Scholar 

  6. Hee MR, Baumal CR, Puliafito CA et al. (1996) Optical coherence tomography of age-related macular degeneration and choroidal neovascularization. Ophthalmology 103: 1260–1270

    PubMed  Google Scholar 

  7. Iida T, Hagimura N, Sato T, Kishi S (2000) Evaluation of central serous chorioretinopathy with optical coherence tomography. Am J Ophthalmol 129: 16–20

    Article  PubMed  Google Scholar 

  8. Kamppeter B, Jonas JB (2003) Central serous chorioretinopathy imaged by optical coherence tomography. Arch Ophthalmol 121: 742–743

    Article  PubMed  Google Scholar 

  9. Lerche RC, Schaudig U, Scholz F et al. (2001) Structural changes of the retina in retinal vein occlusion – imaging and quantification with optical coherence tomography. Ophthalmic Surg Lasers 32: 272–280

    PubMed  Google Scholar 

  10. Massin P, Erginay A, Haouchine B et al. (2002) Retinal thickness in healthy and diabetic subjects measured using optical coherence tomography mapping software. Eur J Ophthalmol 12: 102–108

    PubMed  Google Scholar 

  11. Michael JC, Pak J, Pulido J, de Venecia G (2003) Central serous chorioretinopathy associated with administration of sympathomimetic agents. Am J Ophthalmol 136: 182–185

    Article  PubMed  Google Scholar 

  12. Midena E, Radin PP, Pilotto E et al. (2004) Fixation pattern and macular sensitivity in eyes with subfoveal choroidal neovascularization secondary to age-related macular degeneration. A microperimetry study. Semin Ophthalmol 19: 55–61

    Article  PubMed  Google Scholar 

  13. Pikkel J, Beiran I, Ophir A, Miller B (2002) Acetazolamide for central serous retinopathy. Ophthalmology 109: 1723–1725

    Article  PubMed  Google Scholar 

  14. Rohrschneider K, Glück R, Becker M et al. (1997) Scanning laser fundus perimetry before laser photocoagulation of well defined choroidal neovascularisation. Br J Ophthalmol 81: 568–573

    PubMed  Google Scholar 

  15. Rohrschneider K, Bültmann S, Glück R et al. (2000) Scanning laser ophthalmoscope fundus perimetry before and after laser photocoagulation for clinically significant diabetic macular edema. Am J Ophthalmol 129: 27–32

    Article  PubMed  Google Scholar 

  16. Rohrschneider K, Springer C, Bültmann S, Völcker HE (2005) Microperimetry – comparison between the micro perimeter 1 and scanning laser ophthalmoscope fundus perimetry. Am J Ophthalmol 139: 125–134

    Article  PubMed  Google Scholar 

  17. Sanchez-Tocino H, Alvarez-Vidal A, Maldonado MJ et al. (2002) Retinal thickness study with optical coherence tomography in patients with diabetes. Invest Ophthalmol Vis Sci 43: 1588–1594

    PubMed  Google Scholar 

  18. Schaudig UH, Glaefke C, Scholz F, Richard G (2000) Optical coherence tomography for retinal thickness measurement in diabetic patients without clinically significant macular edema. Ophthalmic Surg Lasers 31: 182–186

    PubMed  Google Scholar 

  19. Schmidt-Erfurth U, Augustin AJ (2001) Kapitel 13: Netzhaut, Aderhaut und Glaskörper. In: Augustin AJ (Hrsg) Augenheilkunde. Springer, Berlin Heidelberg New York Tokio, S 334

  20. Shimura M, Yasuda K, Nakazawa T et al. (2003) Quantifying alterations of macular thickness before and after panretinal photocoagulation in patients with severe diabetic retinopathy and good vision. Ophthalmology 110: 2386–2394

    Article  PubMed  Google Scholar 

  21. Spaide RF, Campeas L, Haas A et al. (1996) Central serous chorioretinopathy in younger and older adults. Ophthalmology 103: 2070–2079; discussion 2079–2080

    PubMed  Google Scholar 

  22. Springer C, Rohrschneider K (2004) Influence of stimulus duration and fixation object in fundus perimetry. In: International Perimetric Society. Barcelona, Spain

  23. Springer C, Bültmann S, Völcker HE, Rohrschneider K (2005) Fundus perimetry with the Micro Perimeter 1 in normal individuals: comparison with conventional threshold perimetry. Ophthalmology 112: 848–854

    Article  PubMed  Google Scholar 

  24. Springer C, Völcker HE, Rohrschneider K (2005) Statische Fundusperimetrie bei Probanden: Microperimeter 1 versus SLO. Ophthalmologe 103: 214–131

    Article  Google Scholar 

  25. Strom C, Sander B, Larsen N et al. (2002) Diabetic macular edema assessed with optical coherence tomography and stereo fundus photography. Invest Ophthalmol Vis Sci 43: 241–245

    PubMed  Google Scholar 

  26. Sunness JS, Schuchard RA, Shen N et al. (1995) Landmark-driven fundus perimetry using the scanning laser ophthalmoscope. Invest Ophthalmol Vis Sci 36: 1863–1874

    PubMed  Google Scholar 

  27. Sunness JS, Applegate CA, Haselwood D, Rubin GS (1996) Fixation patterns and reading rates in eyes with central scotomas from advanced atrophic age-related macular degeneration and Stargardt disease. Ophthalmology 103: 1458–1466

    PubMed  Google Scholar 

  28. Tittl MK, Spaide RF, Wong D et al. (1999) Systemic findings associated with central serous chorioretinopathy. Am J Ophthalmol 128: 63–68

    Article  PubMed  Google Scholar 

  29. Toonen F, Remky A, Janssen V et al. (1995) Microperimetry in patients with central serous retinopathy. Ger J Ophthalmol 4: 311–314

    PubMed  Google Scholar 

  30. Yannuzzi LA (1987) Type-A behavior and central serous chorioretinopathy. Retina 7: 111–131

    PubMed  Google Scholar 

Download references

Interessenkonflikt

Es besteht kein Interessenkonflikt. Der korrespondierende Autor versichert, dass keine Verbindungen mit einer Firma, deren Produkt in dem Artikel genannt ist, oder einer Firma, die ein Konkurrenzprodukt vertreibt, bestehen. Die Präsentation des Themas ist unabhängig und die Darstellung der Inhalte produktneutral.

Author information

Authors and Affiliations

  1. Augenklinik, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 400, 69120 , Heidelberg

    C. Springer, H. E. Völcker & K. Rohrschneider

Authors
  1. C. Springer
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. E. Völcker
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. K. Rohrschneider
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to C. Springer.

Additional information

Mit Unterstützung der Deutschen Forschungsgemeinschaft (DFG Ro 973/11–2).

Vorgestellt auf der 103. Tagung der DOG in Berlin (25.–29.09.2005).

Rights and permissions

Reprints and permissions

About this article

Cite this article

Springer, C., Völcker, H.E. & Rohrschneider, K. Chorioretinopathia centralis serosa – Netzhautfunktion und -morphologie. Ophthalmologe 103, 791–797 (2006). https://doi.org/10.1007/s00347-006-1396-6

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00347-006-1396-6

Schlüsselwörter

Keywords

Search

Navigation