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Pattern-Laser-Trabekuloplastik und Argon-Laser-Trabekuloplastik zur Glaukombehandlung

Pattern laser trabeculoplasty and argon laser trabeculoplasty for treatment of glaucoma

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Zusammenfassung

Einleitung

Die Argon-Laser-Trabekuloplastik (ALT) und die Pattern-Laser-Trabekuloplastik (PLT) sind 2 laserchirurgische Methoden zur Behandlung des Offenwinkelglaukoms, deren Augeninnendruck (IOD)-senkender Effekt in einer retrospektiven Untersuchung verglichen werden soll.

Methoden

Der intraokulare Druck, der beste mit Gläsern korrigierte Visus und die getropfte Glaukommedikation von Patienten, die zwischen Januar 2011 und Dezember 2012 eine ALT oder PLT an unserer Klinik erhielten, wurden ausgewertet.

Ergebnisse

An 22 Augen von 22 Patienten wurde eine ALT durchgeführt (13 rechte, 9 linke Augen; 71,1 ± 1,5 Jahre; 7 Männer, 15 Frauen); 8,2 ± 0,8 Wochen nach ALT zeigte sich eine signifikante IOD-Abnahme von 18,6 ± 0,9 auf 15,3 ± 0,7 mmHg (p < 0,001). Die Anzahl der getropften Glaukommedikamente pro Auge blieb konstant (p = 0,19). Der mittlere bestkorrigierte Visus blieb konstant (p = 0,15). Die PLT wurde an 20 Augen von 20 Patienten durchgeführt (12 rechte, 8 linke Augen; 69,9 ± 2,6 Jahre; 10 Männer, 10 Frauen). 8,3 ± 0,6 Wochen nach erfolgter PLT zeigte sich eine signifikante mittlere IOD-Abnahme von 20,2 ± 1,1 auf 15,6 ± 0,8 mmHg (p < 0,001) bei konstanter getropfter Glaukommedikation (p = 0,08). Der bestkorrigierte Visus blieb konstant (p = 0,59). Die IOD-Senkung war in der ALT- verglichen mit der PLT-Gruppe nicht signifikant unterschiedlich (p = 0,26).

Schlussfolgerung

Die PLT ist wie die ALT eine effektive Methode zur Behandlung von Offenwinkelglaukomen und führt zu einer ähnlich ausgeprägten, signifikanten IOD-Senkung.

Abstract

Introduction

Argon laser trabeculoplasty (ALT) and pattern laser trabeculoplasty (PLT) are two laser surgery methods for treatment of open angle glaucoma and the effect in reducing intraocular pressure (IOP) of these methods was compared in a retrospective study.

Methods

The IOP, the best corrected visual acuity (BCVA) and the eye drop glaucoma medication used by patients who were treated by ALT or PLT in this clinic between January 2011 and December 2012 were compiled and evaluated.

Results

An ALT was carried out on 22 eyes from 22 patients (13 right and 9 left eyes in patients with an average age of 71.1 ± 1.5 years, 7 men and 15 women) and a significant average reduction of IOP from 18.6 ± 0.9 to 15.3 ± 0.7 mmHg (p < 0.001) was observed an average of 8.2 ± 0.8 weeks after ALT. The number of dropped glaucoma medications per eye (p = 0.19) and the mean BCVA both remained constant (p = 0.15). A PLT was carried out on 20 eyes from 20 patients (12 right and 8 left eyes in patients with an average age of 69.9 ± 2.6 years, 10 men and 10 women) and a significant average reduction of IOP from 20.2 ± 1.1 to 15.6 ± 0.8 mmHg (p < 0.001) was observed an average of 8.3 ± 0.6 weeks after PLT. The number of dropped glaucoma medications per eye (p = 0.08) and the mean BCVA both remained constant (p = 0.59). The difference in the reduction of IOP between the ALT and PLT groups was not significant (p=0.26).

Conclusion

Both PLT and ALT are effective methods for treatment of open angle glaucoma and lead to similar significant reductions in IOP.

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Einhaltung ethischer Richtlinien

Interessenkonflikt. C.E. Barbu, W. Rasche, P. Wiedemann, J. Dawczynski und J.D. Unterlauft geben an, dass kein Interessenkonflikt besteht. Alle im vorliegenden Manuskript beschriebenen Untersuchungen am Menschen wurden mit Zustimmung der zuständigen Ethik-Kommission, im Einklang mit nationalem Recht sowie gemäß der Deklaration von Helsinki von 1975 (in der aktuellen, überarbeiteten Fassung) durchgeführt. Von allen beteiligten Patienten liegt eine Einverständniserklärung vor.

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  1. Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Leipzig AöR, Liebigstr. 10–14, 04103, Leipzig, Deutschland

    C.E. Barbu, W. Rasche, P. Wiedemann, J. Dawczynski &  J.D. Unterlauft

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  1. C.E. Barbu
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  2. W. Rasche
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Barbu, C., Rasche, W., Wiedemann, P. et al. Pattern-Laser-Trabekuloplastik und Argon-Laser-Trabekuloplastik zur Glaukombehandlung. Ophthalmologe 111, 948–953 (2014). https://doi.org/10.1007/s00347-014-3036-x

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  • DOI: https://doi.org/10.1007/s00347-014-3036-x

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