Abstract
Purpose
To report the STRATUS optical coherence tomography (STRATUSOCT) findings in a patient with unilateral coloboma-like excavation of the optic disc without pit but secondary retinoschisis, as well as to discuss the possible involved pathophysiologic mechanisms.
Methods
Observational case report. STRATUSOCT findings in a 66-year-old woman with a coloboma-like excavation of the optic disc without pit but secondary retinoschisis encompassing the macular region, along with evidence of a mild epiretinal membrane superonasal to the disc were evaluated.
Results
STRATUSOCT showed signs of a connection between the perineural space and the inner retinal layers on the temporal optic disc border, as well as schisis-like changes extending from the disc to the macula, with cystoid degeneration and two lamellar holes in their nasal portion.
Conclusion
The use of third generation OCT afforded an enhanced visualization of retinal structures, revealing signs of fluid at several distinct levels, as well as deep and superficial inner breaks apart from the schisis cavity. We are unaware of such previous reports, and could find no reference to them in a computerized search using MEDLINE. In addition, our study supports a common pathomechanism for the development of macular complications in optic pits and colobomas.
Notes
Vincent Michael Patella, Carl Zeiss Meditec, Inc., STRATUSOCT: Establishment of Normative Reference Values for Retinal Nerve Fiber Layer Thickness Measurements. 2003. [Cited 18 November 2003]. Available from URL: http://www.zeiss.com.au/C1256C4F002FF302/EmbedTitelIntern/StratusOCT/$File/OCT+Normative+Database+Paper.pdf
References
Blumenthal EZ, Williams JM, Weinreb RN, Girkin CA, Berry CC, Zangwill LM (2000) Reproducibility of nerve fiber layer thickness measurements by use of optical coherence tomography. Ophthalmology 107:2278–2282
Brodsky MC (1998) Congenital anomalies of the optic disc. In: Miller NR, Newman NJ (eds) Walsh and Hoyt’s clinical neuro-ophthalmology, 5th edn. Williams & Wilkins, Buenos Aires, pp 775–823
Brown GC, Shields JA, Goldberg RE (1980) Congenital pits of the optic nerve head. II. Clinical studies in humans. Ophthalmology 87:51–65
Hotta K, Hirakata A, Hida T (1999) Retinoschisis associated with disc coloboma. Br J Ophthalmol 83:124
Krivoy D, Gentile R, Liebmann JM, Stegman Z, Rosen R, Walsh JB et al (1996) Imaging congenital optic disc pits and associated maculopathy using optical coherence tomography [erratum on Arch Ophthalmol 114:840]. Arch Ophthalmol 114:165–170
Lincoff H, Kreissig I (1998) Optical coherence tomography of pneumatic displacement of optic disc pit maculopathy. Br J Ophthalmol 82:367–372
Lincoff H, Lopez R, Kreissig I, Yannuzzi L, Cox M, Burton T (1988) Retinoschisis associated with optic nerve pits. Arch Ophthalmol 106:61–67
Rutledge BK, Puliafito CA, Duker JS, Hee MR, Cox MS (1996) Optical coherence tomography of macular lesions associated with optic nerve head pits. Ophthalmology 103:1047–1053
Sadun AA (2001) Optic disc pits and associated serous macular detachment. In: Ryan SJ, Schachat AP (eds) Retina, Mosby, St Louis, pp 1823–1824
Savell J, Cook JR (1976) Optic nerve colobomas of autosomal-dominant heredity. Arch Ophthalmol 94:395–400
Schuman JS, Hee MR, Puliafito CA, Wong C, Pedut-Kloizman T, Lin CP et al (1995) Quantification of nerve fiber layer thickness in normal and glaucomatous eyes using optical coherence tomography. Arch Ophthalmol 113:586–596
Schuman JS, Pedut-Kloizman T, Hertzmark E, Hee MR, Wilkins JR, Coker JG et al (1996) Reproducibility of nerve fiber layer thickness measurements using optical coherence tomography [commented on Ophthalmology 1997;104:1530–1531]. Ophthalmology 103:1889–1998
Theodossiadis GP, Theodossiadis PG (2001) Optical coherence tomography in optic disc pit maculopathy treated by the macular buckling procedure. Am J Ophthalmol 132:184–190
Walsh FB, Hoyt WF (1969) Clinical neuro-ophthalmology. 3rd edn. Williams & Wilkins, Baltimore
Author information
Authors and Affiliations
Corresponding author
Additional information
The authors do not have any financial, commercial or proprietary interest in the product discussed in this article.
Rights and permissions
About this article
Cite this article
Meirelles, R.L., Aggio, F.B., Costa, R.A. et al. STRATUS optical coherence tomography in unilateral colobomatous excavation of the optic disc and secondary retinoschisis. Graefe's Arch Clin Exp Ophthalmol 243, 76–81 (2005). https://doi.org/10.1007/s00417-004-0956-1
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00417-004-0956-1