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Idiopathic maculopathy in eyes with regressed retinopathy of prematurity

  • Retinal Disorders
  • Published:
Graefe's Archive for Clinical and Experimental Ophthalmology Aims and scope Submit manuscript

Abstract

Background

To describe idiopathic maculopathy in eyes with regressed retinopathy of prematurity, which differs from cicatricial changes in retinopathy of prematurity.

Methods

Setting: institutional. Patients: patients were former preterm infants who had undergone fundus examinations for retinopathy of prematurity between December 1993 and May 2002. Posterior polar cicatricial change was excluded. The medical records of eight eyes (four patients) with photo-documented idiopathic maculopathy were reviewed retrospectively. Main outcome measures: complete ophthalmologic examinations including best corrected visual acuity (BCVA), refractive error, funduscopic examination, fluorescein angiography (FAG), and optical coherence tomography (OCT).

Results

Maculopathy was characterized by depigmented geographic atrophy. FAG showed window defects due to atrophy of retinal pigment epithelium. OCT showed depression in the fovea with retained internal architecture. In all cases patients had retinopathy of prematurity, and all except one had been treated with laser photocoagulation. In the case without laser photocoagulation, maculopathy was observed on the first exam. In the other cases, no maculopathy was observed on the first exam, but was detected after laser photocoagulation. No patient had a family history of hereditary retinal dystrophy. In all cases, maculopathy was noted in both eyes with myopia. BCVA was variable (0.0∼0.82, 0.32 ± 0.32 logMAR). No progression was observed over the course of 8 years.

Conclusion

Idiopathic maculopathy is a rare posterior polar change that differs from the cicatricial changes seen in retinopathy of prematurity, and is independent of prior laser photocoagulation. No progression was observed, and visual prognosis was fair.

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Authors and Affiliations

  1. Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, 110-744, Republic of Korea

    Kyoung Min Lee, Jeong Hun Kim & Young Suk Yu

  2. Seoul Artificial Eye Center, Clinical Research Institute, Seoul National University Hospital, Seoul, 110-744, Republic of Korea

    Kyoung Min Lee, Jeong Hun Kim & Young Suk Yu

Authors
  1. Kyoung Min Lee
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  2. Jeong Hun Kim
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  3. Young Suk Yu
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Corresponding author

Correspondence to Young Suk Yu.

Additional information

A. Funding / Support: None

B. The authors indicate no financial conflict of interest.

C. Contribution of Authors : design of the study (KML,JHK,YSY), conduct of the study (KML,JHK,YSY), collection and management of data (KML,YSY), analysis and interpretation of data (KML,JHK,YSY), preparation of manuscript (KML,JHK,YSY), review or approval of manuscript (KML,JHK,YSY).

D. This study adhered to the Declaration of Helsinki.

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Lee, K.M., Kim, J.H. & Yu, Y.S. Idiopathic maculopathy in eyes with regressed retinopathy of prematurity. Graefes Arch Clin Exp Ophthalmol 248, 1097–1103 (2010). https://doi.org/10.1007/s00417-010-1355-4

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  • DOI: https://doi.org/10.1007/s00417-010-1355-4

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