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Tubulointerstitial nephritis and uveitis in association with Epstein-Barr virus infection

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Abstract

 The case of a 13.5-year-old girl with acute tubulointerstitial nephritis and uveitis (TINU syndrome) is presented. The etiology of this rare syndrome, which in most cases involves female adolescents and usually regresses spontaneously, is still unknown. An infection-triggered pathological immune reaction has been considered to play a role in the pathogenesis of this disorder. Here we report for the first time the association of TINU syndrome and Epstein-Barr virus infection.

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Authors and Affiliations

  1. Klinikum der Christian-Albrechts-Universität, Klinik für Allgemeine Pädiatrie, Schwanenweg 20, D-24105 Kiel, Germany e-mail: p.eggert@pediatrics.uni-kiel.de, Tel.: +49-431-1810/1622, Fax: +49-431-1831, , , , , , DE

    Jochen Grefer, René Santer, Tobias Ankermann & P. Eggert

  2. Department of Ophthalmology, University of Kiel, Kiel, Germany, , , , , , DE

    Sylvia Faul & Bernhard Nölle

Authors
  1. Jochen Grefer
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  2. René Santer
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  3. Tobias Ankermann
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  4. Sylvia Faul
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  5. Bernhard Nölle
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  6. P. Eggert
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Additional information

Received: 4 May 1998 / Revised: 20 August 1998 / Accepted: 26 August 1998

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Grefer, J., Santer, R., Ankermann, T. et al. Tubulointerstitial nephritis and uveitis in association with Epstein-Barr virus infection. Pediatr Nephrol 13, 336–339 (1999). https://doi.org/10.1007/s004670050621

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  • DOI: https://doi.org/10.1007/s004670050621

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