Blood flow rate in the microvasculature of the optic nerve head in primary open angle glaucoma. A new approach☆
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Cited by (38)
Accuracy of peripapillary versus macular vessel density in diagnosis of early to advanced primary open angle glaucoma
2018, Journal Francais d'OphtalmologieCitation Excerpt :An increasing non-linear monotonic relationship was identified between pVD and MD, which did not seem applicable to mVD (Fig. 3). Vascular factors may play an important role in the pathophysiology of glaucoma and previous studies using fluorescein angiography, colour Doppler imaging, confocal scanning laser ophthalmoscopic angiography, single-point and scanning laser Doppler flowmetry or even laser speckle flowgraphy have demonstrated that reduced peripapillary blood flow dynamics was associated with the disease [22–27]. OCT angiography, an innovative and non-invasive diagnostic test assessing the density of the actively flowing vessel network has recently been employed to assess inner retinal vascularization in glaucomatous patients.
Autoregulation and neurovascular coupling in the optic nerve head
2016, Survey of OphthalmologyCitation Excerpt :The main modifiable risk factor in glaucoma patients is elevated intraocular pressure (IOP)1,45,110,118,121; however, a high percentage of individuals with elevated IOP (a condition called ocular hypertension) never develop glaucoma,103 and many glaucoma patients continue to experience disease progression despite lowering IOP to target levels or have no history of elevated IOP–a condition called normal tension glaucoma (NTG).203 Several studies suggest correlations between impaired ocular blood flow and glaucoma.56,60,67,84,85,90,241 In healthy conditions, vascular beds exhibit an intrinsic ability to maintain relatively constant blood flow over a large range of arterial pressures.
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2009, Becker-Shaffer's Diagnosis and Therapy of the Glaucomas: Eighth EditionPrimary open-angle glaucoma patients have reduced levels of blood docosahexaenoic and eicosapentaenoic acids
2006, Prostaglandins Leukotrienes and Essential Fatty AcidsLatanoprost and brimonidine: Therapeutic and physiologic assessment before and after oral nonsteroidal anti-inflammatory therapy
2002, American Journal of OphthalmologyRole of nitric oxide in the control of ocular blood flow
2001, Progress in Retinal and Eye Research
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This study was funded entirely by the authors and/or their institutions.