Cellular interactions with synthetic polymer surfaces in culture
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2015, Colloids and Surfaces B: BiointerfacesCitation Excerpt :Most recently, Ishihara et al. revealed the tight correlation between surface ζ-potential and cell adhesion on a series of novel polymer brush layers [9]. So far, effects of surface chemistry are generally considered secondary to adsorbed serum proteins on substrate surface [10,11]. While exact molecular mechanisms remain unresolved due to the complexity in biomaterial properties, it has been implicated that surface chemistry can modulate both composition and conformation of adsorbed proteins, which in turn recruit distinct integrin receptors on cell surface and control subsequent cellular behaviors [12–14].
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