Autoclavable highly cross-linked polyurethane networks in ophthalmology
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Cited by (22)
A novel gatifloxacin-loaded intraocular lens for prophylaxis of postoperative endophthalmitis
2023, Bioactive MaterialsCitation Excerpt :For this reason, a biofriendly substrate with outstanding mechanical properties is required. Polyurethane (PUR), a versatile material which could reach excellent mechanical properties, have been reported as a potential IOL material in studies, wherein PUR was described to have a high refractive index, excellent mechanical properties, a moderate cell adhesion properties, and it did not display cytotoxicity [40–43]. Moreover, when hydroxyl acrylates are used as blocking agent during PUR synthesis, the product, poly (urethane acrylate) (PUA), displays the advantages of both of its components, namely, the urethane bond and the acrylate functional group.
Materials and methods for microfabrication of microfluidic devices
2021, Microfluidic Devices for Biomedical Applications3D Printing of Polyurethane Biomaterials
2016, Advances in Polyurethane BiomaterialsOptimizing the surface density of polyethylene glycol chains by grafting from binary solvent mixtures
2015, Applied Surface ScienceCitation Excerpt :One of the most important strategies in making non-fouling coatings involves preventing initial bio-adhesion by using a hydrophilic polymeric coating that acts as an interfacial steric barrier between the substrate and the conditioning film forming biomolecules [1,4]. Several molecules such as dextran, chitosan, alginate, hyaluronic acid, mannitol, polyacrylamide, oligo(ethylene glycol) (OEG), PEG and zwitterionic polymers have been demonstrated to resist fouling related processes such as protein adsorption or microbial adhesion [5]. Among the aforementioned molecules, PEG is one of the most widely used and well studied molecules related to non-fouling surfaces.
Materials and methods for the microfabrication of microfluidic biomedical devices
2013, Microfluidic Devices for Biomedical ApplicationsElastomeric biomaterials for tissue engineering
2013, Progress in Polymer ScienceCitation Excerpt :During the next decade, the susceptibility of PUs to biodegradation was extensively researched both in vitro and in vivo, with the latter conducted by routine subcutaneous, intramuscular and intraperitoneal implantation. Evaluations in other more specialized implantation sites, forming more complex implants, have included the cardiovascular system (artificial heart [72], vascular grafts [73–78], and stents [79]) the middle ear (artificial tympanic membrane [80]), the eye (artificial intraocular lenses [81]) the digestive tract (stent-like extensions for the oesophagus [82]) and digestive tract (engineered replacements for the ureter [83] and biliary ducts [84]). In addition to mechanical failures caused by the limited biostability of PUs, the biological toxicity of degradation products of PUs was also found be a serious problem.