Original articleRetinal nerve fiber layer thickness remains unchanged following laser-assisted in situ keratomileusis1☆,
Section snippets
Methods
Patients undergoing LASIK by two of the authors (D.F.B., B.D.S.) were enrolled in this prospective study. One eye was chosen randomly if both eyes were scheduled for surgery. Informed consent was obtained from each subject using a consent form approved by the Institutional Review Board for Human Research of the New York Eye and Ear Infirmary.
Inclusion criteria included absence of ophthalmic disease other than myopia and astigmatism, and no family history of glaucoma. Exclusion criteria included
Results
Twenty eyes of 20 patients were enrolled (7 males, 13 females). Mean patient age was 39.3 ± 9.5 (SD) years (range, 28 to 62 years). Mean preoperative and postoperative spherical equivalent refractive errors were −3.9 ± 1.9 diopters (D) (range, −1.4 to −8.00 D) and −0.3 ± 0.4 D (range, −1.4 to 0.5 D), respectively. Mean spherical equivalent refractive surgical correction was 3.6 ± 1.9 D (range, 1.00 to 8.50 D).
Total mean RNFL and superior, inferior, temporal, and nasal mean RNFL thicknesses
Discussion
Computerized imaging devices offer the potential for reliable, reproducible, objective measurement of structural injury in glaucoma. OCT and SLP provide an assessment of RNFL structure by utilizing different optical techniques. OCT evaluates reflectance of posterior segment structures and incorporates a mathematical algorithm capable of localizing the anterior and posterior limits of the RNFL.8, 11 This provides a direct measurement of RNFL thickness. SLP utilizes the birefringence
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This work was supported in part by the New York Glaucoma Research Institute, New York, NY.
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The authors have no financial interest in any device or technique described in this paper.