Original articleOptical coherence tomography and focal macular electroretinogram in eyes with epiretinal membrane and macular pseudohole☆
Section snippets
Design
This was an observational case series.
Methods
Forty-two eyes of 42 consecutive patients (15 men and 27 women) with an ERM with an MPH were studied. The patients ranged in age from 44 to 87 years (64 ± 9 years, mean ± standard deviation [SD]).
The diagnosis of MPHs was made by ophthalmoscopy, slit-lamp biomicroscopy with a contact lens, fluorescein angiography,8 the Watzke-Allen test,9 and static microperimetry using a scanning laser ophthalmoscope.10 Patients who had a secondary ERM or cataract that affected vision were excluded. Patients
Visual acuity
The median best-corrected visual acuity of the 42 eyes was 20/30 with a range of 20/17 to 20/200. Of the 42 eyes, 22 eyes (52%) had a visual acuity of 20/30 or better, 16 eyes (38%) had a visual acuity of 20/33 to 20/60, and 4 eyes (10%) had a visual acuity of less than 20/60.
Optical coherence tomography
The mean diameter of the MPHs obtained from horizontal and vertical scans ranged from 180 μm to 860 μm with a mean of 437.7 ± 172.8 μm (± SD). The ratio of the short to the long axes of the MPH ranged from 1.0 to 2.8 (1.3
Discussion
Our results showed that there was a wide range of thicknesses of the base of the MPH. The base of an MPH was of normal thickness with a smooth surface in 69% of the eyes, and the remaining eyes showed abnormal thicknesses or irregular surface of the base of the MPHs. We suggest that this variation resulted from different degrees of contraction of the ERM surrounding the MPHs.
Interestingly, we found that the OCT-determined thickness of the base of the MPHs was not linearly correlated with the
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This study was supported by Grant-in-Aids No. 13307048 and No. 14370557 from the Ministry of Education, Science, and Culture, Japan.