New methods of measuring the rate of aqueous flow in man with fluorescein
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2023, Experimental Eye ResearchEffect of aging on heat transfer, fluid flow and drug transport in anterior human eye: A computational study
2020, Journal of Controlled ReleaseCitation Excerpt :Similar, drug transport model was used as mentioned in Section 3.3 with similar governing equations and boundary conditions (Eqs. (14)–(19)). However, the transport parameters such as the diffusion coefficient of the drug (D), tear turnover rate (m), drug clearance rate from the AC (Ka) and initial drug concentration (C0) were used for fluorescein and their values were taken from the literature [45–48]. Fig. 11(a)-(b) show the temporal evolution of average fluorescein concentration in the cornea and the AC of the eye.
No flow through the vitreous humor: How strong is the evidence?
2020, Progress in Retinal and Eye ResearchCitation Excerpt :This means that assuming steady-state loss of dextran from the vitreous, changes in fluorescent intensity within the anterior chamber depends only on the inverse of the aqueous flow rate through the anterior chamber, thereby providing a means for tracking changes in the aqueous flow rate through the anterior chamber. In a separate experiment, Gaul and Brubaker (1986) utilized two independent methods to fluorescently measure the flow rate through the anterior chamber of one eye of a rabbit (Jones and Maurice's ‘corneal deposit’ method (Jones and Maurice, 1966), denoted here method A), while simultaneously employing Johnson and Maurice's vitreal deposit method (Johnson and Maurice, 1984) in the fellow eye (now denoted method B). Specifically, Gaul and Brubaker report the effects of intravenous injection of acetazolamide, the intravenous injection of mannitol, and water ingestion, have on these two independent measurements of aqueous flow rates through the anterior chamber (Gaul and Brubaker, 1986).
Aqueous Humor Dynamics and Intraocular Pressure Elevation
2015, Glaucoma: Second EditionHeparin-modified gelatin scaffolds for human corneal endothelial cell transplantation
2014, BiomaterialsCitation Excerpt :Human corneal endothelial cells (HCECs), which line the inner surface of cornea, are critical for maintaining transparency of the cornea by regulating stromal hydration using ATPase pumps [1,2].
Nitric oxide levels in the aqueous humor vary in different ocular hypertension experimental models
2014, Kaohsiung Journal of Medical Sciences