Recent increase in mortality from byaline membrane disease*
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Cited by (128)
Noninvasive monitoring of gas exchange
2022, Goldsmith's Assisted Ventilation of the Neonate: An Evidence-Based Approach to Newborn Respiratory Care, Seventh EditionAutomation of oxygen titration in preterm infants: Current evidence and future challenges
2021, Early Human DevelopmentCitation Excerpt :We contend that there is a need for: i) rigorously conducted randomised controlled trials of automated oxygen control, ii) a better understanding of the function and comparative performance of contemporary control algorithms, iii) enhancement and individualisation of algorithm performance through adaptation, and iv) application of this technology in low resource settings in which the majority of preterm infants receive care. Oxygen therapy is a cornerstone of management for preterm infants with respiratory insufficiency, and over the years has aimed to overcome the long-recognized consequences of extreme hypoxaemia, including death and neurodevelopmental impairment [1–3]. More recent data from the SpO2 targeting trials assembled by the NeOProM collaborators indicate that even mild hypoxia (SpO2 target range 85–89%) imparts an additional mortality risk, at least in the extremely preterm group [4].
Targeting Arterial Oxygen Saturation by Closed-Loop Control of Inspired Oxygen in Preterm Infants
2019, Clinics in PerinatologyCitation Excerpt :Most extreme premature infants require oxygen supplementation to maintain adequate arterial oxygen levels, and the need for supplemental oxygen can extend for several weeks after birth. Although essential for avoiding the deleterious effects of hypoxia,1–3 excessive arterial oxygen levels have been associated with eye, lung, and central nervous system (CNS) damage.4–9 More recently, clinical trials have shown increased mortality with exposure to lower saturation ranges10,11 and detrimental pulmonary and hemodynamic effects associated with insufficient oxygenation.12–16
Optimal Oxygenation in Extremely Preterm Infants
2018, The Newborn Lung: Neonatology Questions and Controversies, Third EditionNeonatal Respiratory Therapy
2018, Avery's Diseases of the Newborn: Tenth EditionNeonatal Respiratory Therapy
2017, Avery's Diseases of the Newborn, Tenth Edition
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This study was supported in part by a special traineeship BT 259 C2 from the National Institute of Neurological Diseases and Blindness, Public Health Service.
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Address, Department of Pediatrics, The Johns Hopkins Hospital, Baltimore 5, Md.