Elsevier

The Journal of Pediatrics

Volume 57, Issue 4, October 1960, Pages 553-559
The Journal of Pediatrics

Recent increase in mortality from byaline membrane disease*

https://doi.org/10.1016/S0022-3476(60)80083-2Get rights and content

Summary

The “incidence” of fatal hyaline membrane disease in the Johns Hopkins Hospital has been compared for two 5 years periods. During the first, 1944–1948, oxygen was widely used in the premature nursery, beginning 30 to 60 minutes after delivery. The second, 1954–1958, was an era when the concentration of oxygen in the incubators was usually restricted to below 40 per cent. A slight increase in the “incidence” of the disease in the later period makes it evident that low oxygen concentrations after the first 30 minutes were not associated with a decrease in the “incidence” of hyaline membrane disease.

The proportion of autopsies on premature infants showing hyaline membrane disease increased from 21.9 per cent in 1944–1948 to 26.2 per cent in 1954–1958.

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*

This study was supported in part by a special traineeship BT 259 C2 from the National Institute of Neurological Diseases and Blindness, Public Health Service.

*

Address, Department of Pediatrics, The Johns Hopkins Hospital, Baltimore 5, Md.

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