Elsevier

Ophthalmology

Volume 102, Issue 10, October 1995, Pages 1450-1460
Ophthalmology

Prevalence of Age-related Maculopathy in Australia: The Blue Mountains Eye Study

https://doi.org/10.1016/S0161-6420(95)30846-9Get rights and content

Purpose: To examine the prevalence of age-related maculopathy (drusen and retinal pigmentary abnormalities) and end-stage age-related macular degeneration lesions (neovascular maculopathy or geographic atrophy) in a defined older Australian urban population.

Subjects: All noninstitutionalized residents 49 years of age or older who were identified in a door-to-door census of two postcode areas west of Sydney, Australia.

Methods: All participants received a detailed eye examination, including stereoscopic photographs of each macula. Two trained graders used the Wisconsin Age-related Maculopathy Grading System to assess the presence and severity of typical lesions.

Results: A marked age-related increase in all typical lesions of age-related maculopathy and macular degeneration was observed. End-stage age-related macular degeneration was present in 1.9% of the population, rising from 0% among people younger than 55 years of age to 18.5% among those 85 years of age or older. Soft drusen were found in 13.3% of people, with distinct drusen more frequent than indistinct soft drusen. Retinal pigmentary abnormalities were found in 12.6% of people. For end-stage lesions and soft drusen, females had higher age-specific prevalence rates than males, whereas retinal pigmentary abnormalities were more frequent in males, although most of these differences were not significant. Prevalence rates for all lesions were lower (statistically significant for retinal pigmentary abnormalities and soft drusen) than for the United States Beaver Dam Eye Study which examined a similar population.

Conclusions: These data provide detailed prevalence rates for most components of ARM in an Australian population and reinforce the Beaver Dam Eye Study findings for the relative age-specific frequency of age-related macular degeneration components.

References (26)

  • F Jonasson et al.

    Prevalence of ocular disease and blindness in a rural area in the eastern region of Iceland during 1980 through 1984

    Acta Ophthalmol Suppl

    (1987)
  • RA Mitchell

    Prevalence of age related macular degeneration in persons aged 50 years and over resident in Australia

    J Epidemiol Community Health

    (1993)
  • NM Bressler et al.

    The grading and prevalence of macular degeneration in Chesapeake Bay watermen

    Arch Ophthalmol

    (1989)
  • Cited by (0)

    Supported by the Australian Department of Health, Housing and Community Services (RADGAC grant), the Save Sight Institute, University of Sydney, the Ophthalmic Research Institute of Australia and the Western Sector Public Health Unit, NSW Australia.

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