Article for CME CreditConjunctival lymphocytic infiltrates associated with Epstein-Barr virus☆
Section snippets
Patient 1
A 19-year-old man was evaluated for a 1-week history of a red right eye. The patient also had a painful, enlarged right preauricular lymph node and a sore throat. Ocular abnormalities were confined to his right eye. Examination showed his visual acuity to be 20/15, and a salmon-colored mass was present in the conjunctiva inferiorly involving the fornix and extending into the caruncle (Fig 1). The remainder of his examination was unremarkable. A complete blood count showed a 60% lymphocytosis,
Discussion
Epstein-Barr virus has been associated with a variety of ocular diseases, including Parinaud oculoglandular syndrome, conjunctivitis, dry eye, keratitis, uveitis, choroiditis, retinitis, papillitis, and ophthalmoplegia.1, 2, 6 There have been at least three patients previously described with conjunctival masses associated with EBV infections.3, 4, 5 Those cases are similar to our first patient, whereas our second patient is unique, having bilateral conjunctival masses and a transient monoclonal
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Supported in part by the National Institutes of Health (Department Core Grant no. EY06360), Research to Prevent Blindness, Inc., New York, NY, and the Gertrud Kusen Foundation, Bendestorf, Germany.