International Journal of Radiation Oncology*Biology*Physics
External radiotherapy in macular degeneration: Technique and preliminary subjective response
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Radiation therapy for neovascular age-related macular degeneration
2013, International Journal of Radiation Oncology Biology PhysicsCitation Excerpt :Radiation was well tolerated, with cataract developing by 12 months in 1 patient treated with 15 Gy. This landmark paper engendered several additional phase 1/phase 2 studies (Table 1) (31-47). Several drawbacks limit the conclusiveness and generalizability of these early studies.
Proton Beam Irradiation for Neovascular Age-Related Macular Degeneration
2006, OphthalmologyEffect of irradiation on neovascularization in rat skinfold chambers: Implications for clinical trials of low-dose radiotherapy for wet-type age-related macular degeneration
2004, International Journal of Radiation Oncology Biology PhysicsCitation Excerpt :In 1993, Chakravarthy et al. (1) reported a study of the use of low-dose radiotherapy for age-related macular degeneration; during a 12-month follow-up period, 63% of the cases showed no subsequent worsening of visual acuity and 77% showed atrophy of the CNV. Additional clinical trials have produced contradictory results: most replicated the original findings (2–8), but others failed to do so (9, 10). Possible explanations of these contradictory results include differences in the stage of disease, in the evaluation of the therapy, and in the evaluation of the CNV.
The age-related macular degeneration radiotherapy trial (AMDRT): One year results from a pilot study
2004, American Journal of OphthalmologyRadiotherapy in age-related macula degeneration
2002, International Journal of Radiation Oncology Biology PhysicsTreatment of age-related macular degeneration
2000, Clinical Eye and Vision Care