Original articleComparison of Quality-of-Life Instruments in Adults with Strabismus
Section snippets
Methods
The AS-20 consists of 20 questions with two established subscales: psychosocial (10 items) and function (10 items).4 For each AS-20 questionnaire item, a 5-point Likert-type scale is used for responses: never (score 100), rarely (score 75), sometimes (score 50), often (score 25), and always (score 0).4 The VFQ-25 consists of 25 questions in 12 subscales: general health, general vision, ocular pain, near activities, distance activities, vision-specific social function, vision-specific mental
All Strabismus Patients
More patients scored below normal on AS-20 than VFQ-25 composite scores (90% vs 29%; P < .0001; Table 2). On AS-20 subscales, 74% scored below normal on the psychosocial subscale and 75% scored below normal on the function subscale (Table 2). The VFQ-25 subscales with the highest proportion of subnormal scores were: driving (32%), distance activities (25%), and vision-specific role difficulties (21%; Table 2).
Patients With Diplopia
Of the 65 patients with diplopia, significantly more scored below normal on the AS-20
Discussion
Both AS-20 and VFQ-25 questionnaires detected reduced HRQOL in adults with strabismus. The patient-derived, strabismus-specific AS-20 questionnaire detected subnormal HRQOL more often than the vision-specific VFQ-25 questionnaire. The AS-20 questionnaire and component subscales (psychosocial and function) were better able to detect the impact of strabismus on HRQOL, in patients both with and without diplopia.
Our finding that more patients scored below normal thresholds using the AS-20 than
References (8)
- et al.
Impact of severity and bilaterality of visual impairment on health-related quality-of-life
Ophthalmology
(2006) - et al.
Evaluation of the National Eye Institute visual function questionnaire in Graves' ophthalmopathy
Ophthalmology
(2006) - et al.
Development of the 25-item National Eye Institute Visual Function Questionnaire
Arch Ophthalmol
(2001) - et al.
Amblyopia & Strabismus Questionnaire: design and initial validation
Strabismus
(2004)
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Translation and transcultural adaptation of the AS-20 scale to measure quality of life in adults with strabismus in Colombia, a pilot study
2023, Archivos de la Sociedad Espanola de OftalmologiaThe impact of strabismus on psychosocial heath and quality of life: a systematic review
2021, Survey of OphthalmologyDiplopic versus nondiplopic strabismus: effects on functional vision and eye-related quality of life in adolescents
2021, Journal of AAPOSCitation Excerpt :Although several previous studies document reduced quality of life in children and/or adolescents with strabismus,1-4 we are unaware of any evaluating whether strabismus with diplopia differs from strabismus without diplopia. Studies in adults with strabismus have shown greater deficits in function related quality of life domains with diplopia,6 and also that the presence of diplopia following strabismus surgery is associated with failure to improve quality of life.7 Data from the present study provide evidence of the additional impact of diplopia on quality of life in adolescents.
Validation of the French version of the health-related quality of life questionnaire for adult strabismus (AS-20)
2017, Journal Francais d'Ophtalmologie