Original articleFoveal Microstructure on Spectral-Domain Optical Coherence Tomographic Images and Visual Function After Macular Hole Surgery
Section snippets
Subjects and Methods
This prospective study was designed to examine patients with an idiopathic MH who were scheduled to undergo MH surgery. Forty-five patients who underwent pars plana vitrectomy for an MH at the Chiba University Hospital from April 1, 2009 to April 30, 2010 were studied. Cases with traumatic or secondary macular holes, myopic eyes with a refractive error of more than −8.00 diopters, and cases in which the MH was not closed after the primary surgery were excluded.
Two patients were lost to
Postoperative Changes of Visual Acuity, Foveal Sensitivity, and Foveal OCT Findings
The mean preoperative BCVA was 0.72 ± 0.31 logMAR units. The mean postoperative BCVA was 0.51 ± 0.34 logMAR units at 1 month, 0.36 ± 0.28 logMAR units at 3 months, and 0.26 ± 0.25 logMAR units at 6 months. At all postoperative times, the BCVA significantly improved as compared with the preoperative BCVA (P < .0001 for all). The mean preoperative foveal sensitivity was 8.28 ± 4.25 dB. The mean postoperative foveal sensitivity was 11.75 ± 3.37 dB at 1 month, 12.25 ± 3.64 dB at 3 months, and 13.31
Discussion
This study showed that the lengths of both the IS/OS junction defect and the ELM defect were significantly correlated with both the BCVA and the foveal sensitivity at all postoperative times. In addition, our results demonstrated that the length of the IS/OS junction defect was significantly correlated with the length of the ELM defect and that the restoration of the ELM was earlier than that of the IS/OS junction at all times and in all eyes. None of the eyes had a complete restoration of the
Emi Ooka, MD, PhD, graduated from Chiba University School of Medicine, Chiba, Japan, in 2004. She completed her residency at Chiba University Hospital and the Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine. Dr. Ooka's interest is on the treatment of macular diseases including macular hole, epiretinal membrane, and age-related macular degeneration.
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Emi Ooka, MD, PhD, graduated from Chiba University School of Medicine, Chiba, Japan, in 2004. She completed her residency at Chiba University Hospital and the Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine. Dr. Ooka's interest is on the treatment of macular diseases including macular hole, epiretinal membrane, and age-related macular degeneration.