Original articleIntraocular Pressure, Central Corneal Thickness, and Glaucoma in Chinese Adults: The Liwan Eye Study
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Materials and Methods
The detailed study protocol has been reported elsewhere.22 In brief, subjects were enrolled from a population-based study conducted among residents of Liwan District, Guangzhou City, aged 50 years and above using cluster random sampling. Fieldwork was carried out between September 10, 2003 and February 14, 2004.
A standard questionnaire was administered by a trained interviewer. DM and hypertension were defined based on self-reported history of a diagnosis or previous medication use. Height and
Results
In total, 1865 people were identified as eligible in the sampling district. Among them, 1405 (75.4%) were successfully examined. Reasons for nonparticipation included 168 refusals (9%), 66 (3.5%) severely ill or physically disabled, and 226 (12.1%) who could not be contacted after at least 3 home visits. In general, people aged 80 years and over were less likely to participate than other age groups. Among the 1405 subjects, 12 did not have IOP data available. Optical CCT data were missing for
Discussion
This is the first study to provide population-based data on IOP and CCT distribution as well as their determinants in southern China. Both optical and ultrasound pachymetry data are available, allowing direct comparison with most existing studies.
The inter-ethnic comparison of CCT in population studies is summarized in Table 6. Our optical and ultrasound CCT values were 512 ± 29.0 μm and 542 ± 31.4 μm respectively, which were consistent with the results reported by a meta-analysis (510-519 μm
Dandan Wang, MD, graduated from Sun Yat-sen University of Medical Science, Guangzhou, China. She completed her ophthalmology training at the Zhongshan Ophthalmic Center and was certified by the China Board of Ophthalmology in 2005. She underwent further training in glaucoma at the University of California, San Francisco, in 2007. Dr. Wang currently serves as a postdoctoral research associate at the Doheny Eye Institute of the University of Southern California. Her research is mainly focused on
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Dandan Wang, MD, graduated from Sun Yat-sen University of Medical Science, Guangzhou, China. She completed her ophthalmology training at the Zhongshan Ophthalmic Center and was certified by the China Board of Ophthalmology in 2005. She underwent further training in glaucoma at the University of California, San Francisco, in 2007. Dr. Wang currently serves as a postdoctoral research associate at the Doheny Eye Institute of the University of Southern California. Her research is mainly focused on the prevalence of eye disease among Chinese Americans.