Original articleDepression and Visual Functioning in Patients With Ocular Inflammatory Disease
Section snippets
Participants
Consecutive patients between March 29, 2010 and July 19, 2010 seen in the Uveitis and Ocular Inflammatory Disease Clinic at the Francis I. Proctor Foundation, a tertiary care referral center at the University of California, San Francisco, were included in the study. Eligible individuals included patients at least 18 years of age with a diagnosis of noninfectious ocular inflammatory disease, who were English-speaking and able to provide written informed consent. Patients seen at the Francis I.
Results
Of 151 eligible subjects for the study, 31 declined, 8 consented but did not mail in their questionnaires, and 8 consented but had incomplete questionnaires, resulting in 104 consecutive patients in the analysis. Twenty-eight subjects (26.9%) scored greater than 13 on the BDI-II (“depressed group”) and 76 subjects (73.1%) scored 13 or less (“not-depressed group”). There were no significant demographic differences between the depressed and not-depressed groups. Overall, 54.8% of participants
Discussion
Twenty-eight of 104 subjects with ocular inflammatory disease (26.9%) screened positive for depression by the BDI-II in our tertiary practice, which is much higher than 10% in the general population.20 This is in the same range as patients with chronic diseases such as rheumatoid arthritis,23 diabetes,24 cancer,25 and other chronic eye diseases such as retinitis pigmentosa6 and advanced macular degeneration.5 Less is known about depression in patients with ocular inflammatory disease. One
Nisha Acharya, MD, MS, is Director of the Uveitis Service at the F.I. Proctor Foundation and Associate Professor in the Department of Ophthalmology at the University of California, San Francisco. Her research interests include designing and implementing clinical trials and epidemiologic studies in the field of ocular infection and inflammation.
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2023, Survey of OphthalmologyAssociation of Mood Disorders, Substance Abuse, and Anxiety Disorders in Children and Teens With Serious Structural Eye Diseases
2022, American Journal of OphthalmologyVision-Related Quality Of Life And Depression In Brazilian Patients With Toxoplasmic Retinochoroiditis: Ocular Toxoplasmosis, Quality Of Life And Depression
2021, International Journal of Infectious DiseasesCitation Excerpt :Previous studies have demonstrated the impact of uveitis in general health and quality of life of affected individuals (Schiffman RM, Jacobsen G, 2001). In addition to compromised VRQL, increased prevalence of depression has also been observed in patients with noninfectious uveitis (Qian et al., 2012). Infectious uveitis like toxoplasmosis, however, has not been sufficiently investigated.
Whitcup and Nussenblatt’s Uveitis: Fundamentals and Clinical Practice
2021, Whitcup and Nussenblatt's Uveitis: Fundamentals and Clinical PracticeTime Trade-off Utility Values in Noninfectious Uveitis
2019, American Journal of OphthalmologyCitation Excerpt :The dysfunctional thinking associated with depression, in addition to persistent negative thoughts as mentioned previously, may increase patient willingness to give up more time for better health.30,40 Because the prevalence of depression is higher in patients with noninfectious uveitis than the general population, depressive symptoms and dysfunctional attitudes should be monitored in these patients, as they can have a profound, negative effect on quality of life.31,41–43 In regards to trading behavior in the TTO activity, education level was a significant predictor of whether or not patients would trade time for healthy eyes.
Nisha Acharya, MD, MS, is Director of the Uveitis Service at the F.I. Proctor Foundation and Associate Professor in the Department of Ophthalmology at the University of California, San Francisco. Her research interests include designing and implementing clinical trials and epidemiologic studies in the field of ocular infection and inflammation.
Ying Qian, MD, received her medical degree from University of Pennsylvania School of Medicine in Philadelphia and completed her ophthalmology residency at Cole Eye Institute at Cleveland Clinic in Ohio. She completed a uveitis fellowship at the Francis I. Proctor Foundation at University of California San Francisco and will pursue a cornea fellowship at Proctor/UCSF. Her research interests include epidemiological studies in uveitis, corneal infections, and tele-ophthalmology.