Original articleChoroidal Thickness in Nonarteritic Anterior Ischemic Optic Neuropathy
Section snippets
Methods
The hospital-based retrospective observational study analyzed a study group of patients with nonarteritic AION and a control group of patients who attended the hospital for cataract surgery or reasons other than macular or retinal diseases. The ethics committee II of the Medical Faculty Mannheim of the University of Heidelberg approved the study according to the Declaration of Helsinki and all federal laws in Germany.
All study participants underwent a detailed ophthalmologic examination,
Results
The study group included 20 patients (16 men) with unilateral acute nonarteritic AION. The mean age was 66.9 ± 9.8 years (range, 42–80 years), and the mean refractive error was + 1.18 ± 1.93 diopters (range, −1.25 to +5.25 diopters). The study group was differentiated into 11 patients with first manifestations of nonarteritic AION and 9 patients who had attended the hospital with acute nonarteritic AION in the second eye when the first eye had experienced nonarteritic AION several months
Discussion
In our hospital-based study, patients with nonarteritic AION showed significantly thinner macular choroids, after adjusting for age, optic disc diameter, gender, and refractive error, than did the individuals of the control group without fundus or optic nerve disorders. It held true for eyes with acute nonarteritic AION, eyes with previous nonarteritic AION and contralateral eyes (yet) unaffected by nonarteritic AION. Correspondingly, choroidal macular thickness did not differ significantly
Alexander K. Schuster received a Master of Science in Medical Physics from the Medical Faculty Mannheim, Ruprecht-Karls-University Heidelberg, Germany in August 2011 and a medical degree in November 2012. Subsequently, he began his residency in ophthalmology at the University Eye Clinics Mannheim.
References (27)
- et al.
Enhanced depth imaging spectral-domain optical coherence tomography
Am J Ophthalmol
(2008) - et al.
A pilot study of enhanced depth imaging optical coherence tomography of the choroid in normal eyes
Am J Ophthalmol
(2009) - et al.
Enhanced depth imaging optical coherence tomography of the choroid in highly myopic eyes
Am J Ophthalmol
(2009) - et al.
Choroidal thickness in polypoidal choroidal vasculopathy and exudative age-related macular degeneration
Ophthalmology
(2011) The 1994 Von Sallman Lecture: the optic nerve head circulation in health and disease
Exp Eye Res
(1995)- et al.
Subfoveal choroidal thickness: the Beijing Eye Study
Ophthalmology
(2013) - et al.
Choroidal thickness measured by spectral domain optical coherence tomography: factors affecting thickness in glaucoma patients
Ophthalmology
(2011) - et al.
Myopic maculopathy imaged by optical coherence tomography: The Beijing Eye Study
Ophthalmology
(2014) - et al.
Visual acuity and subfoveal choroidal thickness: The Beijing Eye Study
Am J Ophthalmol
(2014) Ischemic optic neuropathy
Prog Retin Eye Res
(2009)
Enhanced depth imaging optical coherence tomography of the choroid in central serous chorioretinopathy
Retina
Comparison of choroidal thickness among patients with healthy eyes, early age-related maculopathy, neovascular age-related macular degeneration, central serous chorioretinopathy, and polypoidal choroidal vasculopathy
Retina
The relationship between retinal and choroidal thickness and visual acuity in highly myopic eyes
Br J Ophthalmol
Cited by (31)
Choroidal Vascular Changes in Arteritic and Nonarteritic Anterior Ischemic Optic Neuropathy
2019, American Journal of OphthalmologyCitation Excerpt :Several previous studies investigated macular and peripapillary choroidal thickness (CT) in patients with NA-AION, showing inconsistent and conflicting results. Some of them reported an increased CT in both the macular26 and peripapillary region,27,28 while others showed a decreased macular29 and peripapillary CT.30 Finally, other studies reported no significant change of CT in eyes with NA-AION.31,32 These disparities may arise from differences in population characteristics, stage of the disease, and techniques used to acquire and analyze OCT images.
Macular choroidal thickness in non-arteritic ischemic optic neuropathy
2016, Archivos de la Sociedad Espanola de OftalmologiaChoroidal Thickness in nonarteritic anterior ischemic optic neuropathy
2015, American Journal of OphthalmologyReply
2015, American Journal of OphthalmologyReply
2015, American Journal of Ophthalmology
Alexander K. Schuster received a Master of Science in Medical Physics from the Medical Faculty Mannheim, Ruprecht-Karls-University Heidelberg, Germany in August 2011 and a medical degree in November 2012. Subsequently, he began his residency in ophthalmology at the University Eye Clinics Mannheim.