LetterPulsatile ocular blood flow is unaffected in type 2 diabetes mellitus
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Case reports
Patients and control subjects from our department were enrolled in this study. Only 1 eye of each participant was included. The patients were divided into four groups as follows: 15 patients with no-DR (no-DR group), 10 patients with nonproliferative DR (non-PDR group), 10 patients with PDR with type 2 diabetes mellitus (PDR group), and 86 controls. The patients were put into the groups based on the findings of slit-lamp biomicroscopy, indirect ophthalmoscopy, fundus photography, and
Comments
The results of the current study demonstrate that the POBF in patients with type 2 diabetes mellitus is unchanged independent of the degree of retinopathy. Schmidt et al have reported that ocular pulse amplitude, a hemodynamic parameter reflecting choroidal blood flow, is unchanged in patients with type 1 diabetes mellitus.1 The total choroidal blood flow measured by POBF may remain unaffected as diabetes and DR develop and progress.
Using the original Langham OBF system, Langham et al reported
Acknowledgements
This study was supported by Grants-in-Aid for Encouragement of Young Scientists (B) 15790970 (FM) and for Scientific Research (C) 14571652 (AY) from The Ministry of Education, Culture, Sports, Science and Technology, Japan.
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