Retinal nerve fiber layer structure abnormalities in early Alzheimer's disease: Evidence in optical coherence tomography
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Acknowledgements
This research was supported by the National Natural Science Foundation of China (30772288) and Beijing Municipal Natural Science Foundation (7082043).
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2022, Psychiatry Research - NeuroimagingCitation Excerpt :In the literature, the number of studies that investigated retinal and neural network alterations with the OCT method has been increasing. These studies were mostly conducted on neurodegenerative diseases such as Alzheimer's and Parkinson's diseases, and multiple sclerosis, and retinal degeneration was identified, consistent with the clinical presentation of the disease (Kemenyova et al., 2014, Almarcegui et al., 2010, Lu et al., 2010, Inzelberg et al., 2004). Thus, the retinal layer has been considered a significant anatomical structure where degeneration could be monitored (Kemenyova et al., 2014, Almarcegui et al., 2010, Lu et al., 2010, Inzelberg et al., 2004).