Original articleNine-year incidence of lens opacities in the Barbados Eye Studies☆
Section snippets
Materials and methods
The BESs, funded by the National Eye Institute, are a series of population-based investigations on the prevalence, incidence, progression, and risk factors for major eye diseases in the predominantly black population of Barbados. The studies began with a prevalence phase, The Barbados Eye Study15 (BES; 1987–1992), which included a random sample of Barbadian-born citizens, 40 to 84 years of age, with 84% participation. Of the 4631 BES participants completing examinations at the study site, 4314
Results
The mean age of the 2793 BISED II participants at baseline was 56 years, and 41% were male. Table 1 compares baseline characteristics between the BISED II participants and those who did not participate because of death or other reason. As compared with the participants, nonparticipants were older (mean age, 69.6 and 58.0 years for the deceased and other group, respectively), as expected. Results from univariate analyses indicated that these groups also had lower education and were more likely
Discussion
The BESs provide the first data, to our knowledge, on the long-term patterns and occurrence of lens opacities in a predominantly black population. Our results revealed a significantly higher 9-year incidence of all lens changes, and particularly cortical opacities, in black than in white participants, despite the small number in the latter group. After 9 years of follow-up, approximately one third of the black participants developed cortical opacities and over two fifths developed nuclear
Acknowledgements
The authors thank the Barbados Eye Studies participants and the Ministry of Health, Barbados, for their roles in the study.
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Cataract in the Adult Eye Preferred Practice Pattern®
2017, OphthalmologyRisk factors associated with incident cataracts and cataract surgery in the age-related eye disease study (AREDS): AREDS report number 32
2011, OphthalmologyCitation Excerpt :Although the AREDS population was 96% white, race was found to be significantly associated with the incidence of cortical cataract, with a decreased risk in white participants compared with nonwhite participants, who were mostly black. This finding agrees with data from the Barbados Eye Study, which studied a population that was 93% black and found higher risk of cortical opacities (relative risk, 3.2; 95% CI, 1.7–6.2) among black participants compared with white participants.33 Similarly, the Salisbury Eye Evaluation (SEE) project, in which 26.4% of the population was black, showed a higher risk of cortical cataract in black participants than white participants (odds ratio [OR], 4.0; 95% CI, 3.3–4.8).35
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Manuscript no. 230094.
Supported by the National Eye Institute, Bethesda, Maryland (grant nos.: EY07625 and EY07617).