Original articlePellucid marginal corneal degeneration☆
Section snippets
Materials and methods
We retrospectively reviewed the charts of 116 eyes of 58 patients with PMCD seen between January 1990 and December 2002 in the Cornea Service at L.V. Prasad Eye Institute, Hyderabad, India. All of these cases were diagnosed as PMCD based on the presence of corneal thinning with ectasia of the normal cornea above or below the area of thinning, with no evidence of scarring, vascularization, or lipid deposition and typical topographic features whenever topography was evaluated.
A detailed history,
Results
The series included 45 males (77.6%) and 13 females (22.4%). All cases were bilateral. In one eye, no clinical features of PMCD were seen, but the diagnosis of PMCD was made based on the presence of typical topographic features. The age of the patients ranged from 8 to 66 years, with a mean of 34.0±14.8. One patient (1.7%) had associated vernal keratoconjunctivitis (VKC), 1 (1.7%) had Marfan's syndrome, and 1 (1.7%) had ocular hypertension. The degree of astigmatism was <5.0 diopters (D) in 19
Discussion
To the best of our knowledge, this is the largest series of PMCD reported in the literature. Earlier reports are in the European literature, and the authors have used various terms, including pellucid marginal dystrophy, pellucid marginal degeneration, marginal degeneration of cornea, and cornea piriformis. This clinical entity is one of the most common causes of peripheral corneal thinning.
In most of the published series, no gender predilection has been found. However, a recent article
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Manuscript no. 220917.