Original articleA 3-dimensional ultrasound C-scan imaging technique for optic nerve measurements☆
Section snippets
Materials and methods
Approval to conduct this study was given by The New York Eye & Ear Infirmary Institutional Review Board. Prior written, informed consent was obtained from each subject. Thirty-eight normal eyes (21 male and 17 female) of 32 healthy adult subjects were randomly selected to undergo 3DUS using a 10-MHz linear probe attached to a 3D i-scan Ultrasound Tomography System (Ophthalmic Technologies Inc., Toronto, Canada). Subjects had no known ocular or systemic diseases. After instillation of a topical
Results
Of the 38 normal eyes included in the study, optic nerve measurements could be reliably determined in only 23 (15 male and 8 female), or 61% of eyes. This is because the 3-dimensional scans of 15 eyes had motion artifacts, which are caused by eye movement during the 7.5-second scanning time, and the resulting 3-dimensional image becomes too distorted and useless for measurement purposes.
The age of subjects ranged from 24 to 82 years. These subjects had no known ocular or systemic disease. Their
Discussion
The advent of 3DUS has tremendously enhanced the potential of B-scan ultrasonography. In a clinical setting, a single scan devoid of motion artifact would suffice to generate a useful 3-dimensional image block for optic nerve measurements. Using this block, the optic nerve can now be traced and documented along its path in the orbit, and a coronal slice of the nerve can be imaged at a chosen point behind the globe. In the 23 eyes, a coronal image of the optic nerve appeared as a central core.
Acknowledgements
The authors thank Dr Guo-Pei Yu for providing statistical assistance.
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Manuscript no. 230395.
Dr Finger's research is supported by The EyeCare Foundation, New York, New York, and Research to Prevent Blindness, New York, New York.
The authors have no proprietary interest in the study.