Original ArticleMorphology and Long-term Changes of Choroidal Vascular Structure in Highly Myopic Eyes with and without Posterior Staphyloma
Section snippets
Patients and Methods
The medical records of 420 eyes of 212 patients with high myopia (≥6 D, or axial length ≥ 26.5 mm) who were examined in our high myopia clinic at the Tokyo Medical and Dental University and had had indocyanine green angiography were retrospectively analyzed. Indocyanine green angiography was routinely performed at their initial examination in our high myopia clinic. Of these, 321 eyes of 195 myopic patients were included in the study. Excluded were 75 patients (93 eyes) with expanding areas of
Results
Of the 195 patients, 64 were men and 131 were women, and their mean (± standard deviation) age was 47.2±15.6 years (range, 7–81). Six eyes were pseudophakic, and the refractive error in the remainder ranged from −5.0 to −32.0 D, with a mean of −14.1±4.8 D. Mean axial length was 29.2±1.8 mm (range, 25.2–33.6). The 321 eyes were divided into 2 groups: 210 eyes with posterior staphyloma and 111 eyes without posterior staphyloma. Mean intraocular pressure (IOP) in the highly myopic group did not
Discussion
These results demonstrate that the choroidal vascular pattern in highly myopic eyes shows some specific features. The normal choroidal flush was absent in a high percentage of eyes, and the entry site of posterior ciliary arteries into the choroid was displaced toward the periphery. There were fewer large choroidal veins in the posterior fundus, and the remaining choroidal veins showed marked variations in their diameter. These findings were significantly more common in eyes with posterior
Acknowledgment
The authors thank Prof Duco Hamasaki for his critical discussion and final manuscript revision.
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Manuscript no. 2006-792.
Supported in part by the Japan Society for the Promotion of Science, Tokyo, Japan (research grant nos. 16390495, 17591823).
The authors do not have financial interest in any products/drugs discussed in the article.