Original articleMortality and Ocular Diseases: The Beijing Eye Study
Section snippets
Patients and Methods
The Beijing Eye Study is a population-based study in northern China. It was carried out in 4 communities in the urban district of Haidian in the north of central Beijing and in 3 communities in the village area of Yufa of the Daxing District south of Beijing. The study has been described in detail recently.40, 41 The Medical Ethics Committee of the Beijing Tongren Hospital approved the study protocol and all participants gave informed consent, according to the Declaration of Helsinki. At the
Results
Of the 4439 subjects examined in 2001 and invited for reexamination in 2006, 3251 (73.2%) subjects returned for the follow-up examination, whereas 143 (3.2%) subjects were dead and 1045 (23.5%) subjects were alive but did not agree to be reexamined. Cerebrovascular events were the most common cause of death (n = 41; 29%), followed by malignancies (n = 37; 26%), heart disorders (n = 31; 22%), and other causes (n = 34; 24%) such as nonmalignant lung diseases (n = 6), and liver (n = 3) and kidney
Discussion
In the adult Chinese population with an age of 40 years or more and living in the Greater Beijing area, 3.2% of subjects died during a follow-up period of 5 years. Besides the systemic parameters of higher age (P<0.001), male gender (P = 0.01), lower level of education (P<0.001), and smoking (P = 0.02), ocular parameters with a significant association with mortality were level of diabetic-like retinopathy (P = 0.036), presence of angle-closure glaucoma (P = 0.013), and presence of
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Manuscript no. 2008-898.
Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article.
Supported by the Beijing Natural Science Foundation, Beijing, China.