Original articleCorrelation of Nuclear Cataract Lens Density Using Scheimpflug Images with Lens Opacities Classification System III and Visual Function
Section snippets
Patients and Methods
One hundred ten patients with nuclear cataract, diagnosed on slit-lamp examination, were enrolled. Subjects were recruited between May 2007 and March 2008 at the Grewal Eye Institute, Chandigarh, India. None of the patients had had any previous ocular surgery, laser treatments, or a history of any ocular disease other than age-related cataract. All patients underwent slit-lamp examination and dilated fundus examination. Institutional Review Board approval was obtained and the study was
Results
A total of 110 participants were enrolled. Their mean age was 67.1±9.8 years (range, 40–84). The study population was composed of 60 females and 50 males. The mean BCVA was 0.13±0.11 (range, 0–0.4). The mean NO score calculated using LOCS III was 3.73±1.49 (range, 1–6.4) and the mean NC grading was 3.82±1.37 (range, 1.3–6.4). The mean average lens density obtained using ImageJ software (measured in pixel intensity units) was 63.58±20.83 (range, 36.6–110.5) and the mean nuclear lens density
Discussion
The lack of objective measurements of lens opacity is an impediment to clinical trials and studies on cataract formation and growth.35 A standardized grading system for cataracts is needed to accurately reflect the severity of cataract at past appointments, because patients are often seen by a different doctor at each visit. This would be especially useful in longitudinal studies on nuclear cataract. Pei et al22 in a similar study recently reported that the lens density assessed on Pentacam
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Manuscript no. 2008-1481.
Financial Disclosure(s): The authors have no proprietary or commercial interest in any of the materials discussed in this article.