Original articleDeterminants and Two-Year Change in Anterior Chamber Angle Width in a Chinese Population
Section snippets
Materials and Methods
Random cluster sampling was used to identify adults aged ≥35 years resident in the Yuexiu District of Guangzhou, China, for participation in a study of presbyopia in December 2008. Details of the recruitment and examination procedures have been reported9 and are summarized in this article for reference. During door-to-door household visits, data on all persons aged ≥35 years were collected, including name, sex, and age. Examinations including measurement of binocular near visual acuity,
Results
A total of 745 persons underwent biometric testing in both 2008 and 2010. Subjects not present for testing in 2010 did not differ from those available for testing with regard to baseline age in 2008, sex, weight, height, spectacle wear, or any of the measured ocular biometric parameters (right eye ACD, AL, IT750, corneal thickness, corneal curvature, iris curvature, lens thickness, AOD500, LV, pupil size, or ACW) (Table 1, available at http://aaojournal.org). The number of subjects successfully
Discussion
This is the first population-based, longitudinal study of quantitative measures of anterior chamber angle width in Chinese persons, who have a high prevalence of primary angle-closure diseases.14, 15 We found that persons with younger age at baseline and biometric characteristics of a less-crowded angle were generally at risk for greater 2-year decreases in angle width as measured by AOD500 and ARA. A recent cross-sectional study in Singapore analyzed similar quantitative angle measures in a
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Manuscript no. 2012-420.
Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article.
Supported by the World Health Organization, Geneva, Switzerland (under National Institutes of Health [Bethesda, MD] contract number N01-EY-2103) and the Fundamental Research Funds for the State Key Laboratory.