Isolated Oculomotor Nerve Palsy in Churg-Strauss Syndrome

Hiromasa TSUDA; Hiroshi ISHIKAWA; Toru MAJIMA; Umihiko SAWADA; Tomohiko MIZUTANI

doi:10.2169/internalmedicine.44.638

CASE REPORTS

Isolated Oculomotor Nerve Palsy in Churg-Strauss Syndrome

Hiromasa TSUDA, Hiroshi ISHIKAWA, Toru MAJIMA, Umihiko SAWADA, Tomohiko MIZUTANI

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Keywords: allergic granulomatous angiitis, Churg-Strauss syndrome, magnetic resonance imaging, midbrain infarction, oculomotor nerve, perinuclear antineutrophil cytoplasmic antibody (p-ANCA)

JOURNAL OPEN ACCESS

2005 Volume 44 Issue 6 Pages 638-640

DOI https://doi.org/10.2169/internalmedicine.44.638

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Abstract

A 30-year-old man with bronchial asthma complained of horizontal diplopia. Partial oculomotor nerve palsy with restrictions of elevation and adduction, and mydriasis was observed in the left eye. Cranial magnetic resonance imaging demonstrated an infarct lesion in the territory of the left superior median mesencephalic branch of the posterior cerebral artery. Based on bronchial asthma, hypereosinophilia, mononeuropathy multiplex, pulmonary eosinophilia and positive perinuclear antineutrophil cytoplasmic antibody in the serum, the patient was diagnosed as having Churg-Strauss syndrome. This is the first case of oculomotor nerve palsy due to midbrain infarction associated with Churg-Strauss syndrome.

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