Surgical treatment of submacular hemorrhage associated with idiopathic polypoidal choroidal vasculopathy

Am J Ophthalmol. 1999 Aug;128(2):147-54. doi: 10.1016/s0002-9394(99)00078-1.

Abstract

Purpose: To report the visual outcome of surgical treatment of submacular hemorrhage associated with idiopathic polypoidal choroidal vasculopathy.

Methods: Eight eyes of eight consecutive patients with thick submacular hemorrhages associated with idiopathic polypoidal choroidal vasculopathy were treated with pars plana vitrectomy and tissue plasminogen activator-assisted removal of subretinal blood (December 1995 to September 1997) or intravitreal 100% sulfur hexafluoride gas injection without tissue plasminogen activator (October 1997 to March 1998).

Results: Postoperatively, laser treatment was performed for active polypoidal lesions outside the foveal avascular zone in four eyes. A retinal pigment epithelial tear was seen outside the foveal avascular zone in three eyes, and one eye developed a retinal detachment. The best-corrected visual acuity improved (by 3 or more lines) or stabilized in seven of the eight eyes. Four eyes had a final best-corrected visual acuity of 20/40 or better, and three eyes had a final best-corrected visual acuity of 20/50 to 20/200. In one eye, the visual acuity decreased from 20/100 to 20/500 because of the development of a subfoveal neovascular membrane. The membrane was excised, and histologic examination showed fibrovascular tissue between the retina and retinal pigment epithelium (type 2 pattern).

Conclusions: Surgical intervention may be of benefit in eyes with submacular hemorrhage associated with idiopathic polypoidal choroidal vasculopathy.

Publication types

  • Case Reports
  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Choroid / blood supply*
  • Choroid / pathology
  • Choroid Diseases / complications*
  • Choroid Diseases / diagnosis
  • Choroid Diseases / drug therapy
  • Choroid Diseases / surgery
  • Female
  • Fibrinolytic Agents / therapeutic use
  • Fluorescein Angiography
  • Follow-Up Studies
  • Fundus Oculi
  • Humans
  • Injections
  • Laser Coagulation
  • Macula Lutea / pathology
  • Macula Lutea / surgery*
  • Male
  • Middle Aged
  • Postoperative Complications / diagnosis
  • Postoperative Complications / surgery
  • Reoperation
  • Retina
  • Retinal Hemorrhage / diagnosis
  • Retinal Hemorrhage / drug therapy
  • Retinal Hemorrhage / etiology
  • Retinal Hemorrhage / surgery*
  • Retrospective Studies
  • Sulfur Hexafluoride / therapeutic use
  • Tissue Plasminogen Activator / therapeutic use
  • Vitrectomy
  • Vitreous Body

Substances

  • Fibrinolytic Agents
  • Tissue Plasminogen Activator
  • Sulfur Hexafluoride