Homocysteine, B vitamins, and coronary artery disease

Med Clin North Am. 2000 Jan;84(1):215-37, x. doi: 10.1016/s0025-7125(05)70215-7.

Abstract

This article discusses the metabolism of homocysteine, factors affecting its plasma level, and the evidence for its role in the pathogenesis of vascular disease. The treatment of hyperhomocysteinemia and its possible impact on vascular disease prevention and progression are described also.

Publication types

  • Review

MeSH terms

  • Clinical Trials as Topic
  • Coronary Artery Disease / etiology*
  • Coronary Artery Disease / prevention & control
  • Folic Acid / administration & dosage
  • Humans
  • Hyperhomocysteinemia / complications*
  • Hyperhomocysteinemia / etiology
  • Myocardial Infarction / etiology*
  • Myocardial Infarction / prevention & control
  • Recurrence
  • Risk Factors
  • Vitamin B Deficiency / complications*
  • Vitamin B Deficiency / etiology

Substances

  • Folic Acid