Indocyanine green angiographic findings in choroidal hemangiomas: A study of 75 cases

Ophthalmologica. 2000;214(4):246-52. doi: 10.1159/000027499.

Abstract

Indocyanine green (ICG) angiography is a new diagnostic modality that was suggested, in small series, to provide a typical angiographic pattern in cases of choroidal hemangioma. Our study, through an exceptionally large series of 75 patients, assessed in a prospective way whether a typical ICG pattern of choroidal hemangioma exists and what would be its possible variations. The most constant feature is the sequence of the different ICG angiographic phases. The arterial phase demonstrates the filling of intratumoral vessels on a hypofluorescent tumoral background. During the venous phase, the hemangioma reaches a stage of maximal ICG-A fluorescence, with superimposed hyper- and hypofluorescent spots. Sturge-Weber cases have also extratumoral hyperfluorescent spots. The late phase shows a hypofluorescent lesion with residual hyperfluorescent caverns and a well-delineated, but complex border structure.

Publication types

  • Comparative Study

MeSH terms

  • Choroid / pathology*
  • Choroid Neoplasms / diagnosis*
  • Diagnosis, Differential
  • Female
  • Fluorescein Angiography*
  • Fluorescent Dyes* / administration & dosage
  • Fundus Oculi
  • Hemangioma, Capillary / diagnosis*
  • Humans
  • Indocyanine Green* / administration & dosage
  • Injections, Intravenous
  • Male
  • Middle Aged
  • Retrospective Studies

Substances

  • Fluorescent Dyes
  • Indocyanine Green