No-anesthesia clear corneal phacoemulsification versus topical and topical plus intracameral anesthesia. Randomized clinical trial

J Cataract Refract Surg. 2001 Oct;27(10):1643-50. doi: 10.1016/s0886-3350(01)00793-3.

Abstract

Purpose: To compare the intraoperative pain scores during clear corneal phacoemulsification under no anesthesia, topical anesthesia, and topical plus intracameral anesthesia.

Setting: Dr. Agarwal's Eye Hospital and Eye Research Center, Chennai, India.

Methods: Seventy-five patients were randomized to have phacoemulsification under no anesthesia, topical anesthesia, or topical plus intracameral anesthesia. Uncooperative or illiterate patients and those with hard cataract, a shallow anterior chamber, or small pupils were excluded. A protocol was established for supplemental anesthesia in case of breakthrough pain during the surgery. Each patient was asked to grade the overall severity of intraoperative pain immediately after surgery on a 10-point visual analog scale. Also evaluated were the general discomfort during surgery, discomfort from the microscope lights, surgeon stress during surgery, and total surgical time. Comparison among the 3 groups was performed using an analysis of variance.

Results: No supplemental anesthesia was required in any group. No significant difference was noted in the mean scores of the subjective sensation of pain with or without topical anesthesia (P =.610). The mean scores of patient discomfort from the microscope lights and surgical time were also statistically insignificant. Patient discomfort and surgeon stress during surgery were significantly greater in the no-anesthesia group than in the topical and topical plus intracameral groups (P =.0235 and P = 0.0206, respectively).

Conclusion: No-anesthesia clear corneal phacoemulsification was performed by a highly experienced, skilled surgeon without causing an unacceptable level of pain. However, this technique is not suitable for every cataract surgeon or patient.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Anesthesia, Local / methods*
  • Anesthetics, Local / administration & dosage*
  • Anterior Chamber / drug effects*
  • Cornea / surgery*
  • Double-Blind Method
  • Female
  • Humans
  • Lens Implantation, Intraocular
  • Lenses, Intraocular
  • Lidocaine / administration & dosage
  • Male
  • Middle Aged
  • Pain Measurement
  • Patient Satisfaction
  • Phacoemulsification / methods*
  • Prospective Studies
  • Silicone Elastomers
  • Surveys and Questionnaires

Substances

  • Anesthetics, Local
  • Silicone Elastomers
  • Lidocaine