Sequential multifocal electroretinogram findings in a case of Purtscher-like retinopathy

Am J Ophthalmol. 2002 Jul;134(1):125-8. doi: 10.1016/s0002-9394(02)01474-5.

Abstract

Purpose: To report the multifocal electroretinographic findings of a patient with pancreatitis-associated Purtscher-like retinopathy.

Design: Observational case report.

Methods: A 20-year-old man with a history of alcohol abuse and acute pancreatitis underwent multifocal electroretinography (mfERG; 103-scaled hexagons, 8-minute recording time) at 1 week, 4 weeks, and 6 months after the onset of the retinopathy.

Results: At 1 week, the patient had extensive cotton- wool spots in the posterior pole bilaterally, and visual acuity was significantly reduced. Both the A-waves and B-waves of the mfERG were depressed in the corresponding areas. At 4 weeks, neither visual acuity nor mfERG showed improvement, although the cotton-wool spots had resolved. Interestingly, at 6 months, visual acuity had improved significantly in the left eye, consistent with increased ratios of mfERG responses for the central area.

Conclusion: There was no selective reduction of b-waves of the mfERG as anticipated in isolated inner retinal pathology. In this case, both the A-waves and B-waves were reduced, suggesting damage to both outer and inner retinal layers.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acute Disease
  • Adult
  • Electroretinography / methods*
  • Humans
  • Male
  • Pancreatitis / complications
  • Pancreatitis / physiopathology
  • Retina / physiology*
  • Retinal Diseases / etiology
  • Retinal Diseases / physiopathology*
  • Time Factors
  • Visual Acuity