Evaluation of limbal conjunctival autograft and low-dose mitomycin C in the treatment of recurrent pterygium

Ophthalmic Surg Lasers Imaging. 2003 May-Jun;34(3):193-6.

Abstract

Background and objective: To assess the effectiveness of limbal conjunctival autograft and low-dose mitomycin C in the treatment of recurrent pterygium.

Patients and methods: Thirty-four eyes with recurrent pterygium underwent surgical excision followed by the intraoperative application of low-dose (0.05%) mitomycin C and the use of limbal conjunctival autograft. All patients were observed for at least 18 months for any complications, including recurrences.

Results: Neither recurrences nor serious complications were recorded. Visual acuity improved significantly (P < .05) in eyes with pterygium extending 3 mm or more beyond the limbus.

Conclusion: Simple excision and low-dose mitomycin C followed by limbal conjunctival autograft is a safe and effective way of treating recurrent pterygium.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Antibiotics, Antineoplastic / administration & dosage*
  • Combined Modality Therapy
  • Conjunctiva / transplantation*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mitomycin / administration & dosage*
  • Prospective Studies
  • Pterygium / drug therapy*
  • Pterygium / surgery*
  • Recurrence
  • Transplantation, Autologous
  • Treatment Outcome
  • Visual Acuity

Substances

  • Antibiotics, Antineoplastic
  • Mitomycin