Epidermodysplasia verruciformis human papillomavirus types and carcinoma of the conjunctiva: a pilot study

C Ateenyi-Agaba; E Weiderpass; A Smet; W Dong; M Dai; B Kahwa; H Wabinga; E Katongole-Mbidde; S Franceschi; M Tommasino

doi:10.1038/sj.bjc.6601743

Epidermodysplasia verruciformis human papillomavirus types and carcinoma of the conjunctiva: a pilot study

Br J Cancer. 2004 May 4;90(9):1777-9. doi: 10.1038/sj.bjc.6601743.

Authors

C Ateenyi-Agaba¹, E Weiderpass, A Smet, W Dong, M Dai, B Kahwa, H Wabinga, E Katongole-Mbidde, S Franceschi, M Tommasino

Affiliation

¹ Department of Ophthalmology, Makerere University, PO Box 7072, Kampala, Uganda.

Abstract

A total of 21 squamous-cell carcinoma of the conjunctiva (SCC) and 22 control subjects had conjunctival samples tested for human papillomavirus (HPV) types using PCR-based assays. Epidermodysplasia verruciformis HPV types were found in 86% of SCC cases and 36% of control subjects (Odds ratio=12.0), suggesting a role of HPVs in the aetiology of SCC.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Blotting, Southern
Carcinoma, Squamous Cell / virology*
Conjunctival Neoplasms / virology*
DNA Primers
Epidermodysplasia Verruciformis / complications
Epidermodysplasia Verruciformis / genetics*
Epidermodysplasia Verruciformis / pathology
Humans
Middle Aged
Papillomavirus Infections / complications*
Papillomavirus Infections / genetics
Papillomavirus Infections / pathology
Pilot Projects
Polymerase Chain Reaction

Substances

DNA Primers