Abstract
Purpose:
To report a case of hypopyon uveitis associated with systemic lupus erythematosus and antiphospholipid antibody syndrome.
Methods:
Interventional case report: a 49-year-old woman with a history of systemic lupus erythematosus and antiphospholipid antibody syndrome presented with sudden onset of pain, redness, photophobia, and decreased vision in the left eye. Examination revealed hypopyon uveitis and vaso-occlusive retinopathy.
Results:
Following treatment with intravenous steroids and cyclophosphamide, the patient's vision improved from CF to 20/80 with no inflammation 6 months following initial presentation.
Conclusions:
In this case, systemic lupus and antiphospholipid syndrome were associated with hypopyon uveitis. Prompt treatment with systemic immunosuppressive therapy resulted in improvement in the hypopyon uveitis and vaso-occlusive retinopathy.
MeSH terms
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Antiphospholipid Syndrome / complications*
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Antiphospholipid Syndrome / diagnosis
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Antiphospholipid Syndrome / drug therapy
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Cyclophosphamide / therapeutic use
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Drug Therapy, Combination
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Female
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Fluorescein Angiography
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Glucocorticoids / therapeutic use
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Humans
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Immunosuppressive Agents / therapeutic use
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Lupus Erythematosus, Systemic / complications*
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Lupus Erythematosus, Systemic / diagnosis
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Lupus Erythematosus, Systemic / drug therapy
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Middle Aged
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Retinal Artery Occlusion / diagnosis
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Retinal Artery Occlusion / drug therapy
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Retinal Artery Occlusion / etiology
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Retinal Vein Occlusion / diagnosis
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Retinal Vein Occlusion / drug therapy
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Retinal Vein Occlusion / etiology
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Uveitis, Suppurative / diagnosis
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Uveitis, Suppurative / drug therapy
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Uveitis, Suppurative / etiology*
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Vision Disorders / etiology
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Visual Acuity
Substances
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Glucocorticoids
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Immunosuppressive Agents
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Cyclophosphamide