Abstract
Purpose:
To report one case of retinal pigment epithelium tear following intravitreal bevacizumab injection for neovascular age-related macular degeneration.
Methods:
A 59-year-old patient presented with occult choroidal neovascularization associated with a serous pigment epithelial detachment secondary to age-related macular degeneration. The patient was treated with an intravitreal injection of bevacizumab.
Results:
The patient developed a retinal pigment epithelium tear 60 days following the intravitreal injection.
Conclusions:
This report describes the development of retinal pigment epithelium tear after intravitreal bevacizumab injection. Future studies should be performed to evaluate which subtypes of lesions are most susceptible to this potential devastating visual complication.
MeSH terms
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Angiogenesis Inhibitors / administration & dosage
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Angiogenesis Inhibitors / adverse effects*
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Antibodies, Monoclonal / administration & dosage
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Antibodies, Monoclonal / adverse effects*
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Antibodies, Monoclonal, Humanized
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Bevacizumab
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Choroidal Neovascularization / complications
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Choroidal Neovascularization / drug therapy
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Diagnosis, Differential
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Fluorescein Angiography
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Follow-Up Studies
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Fundus Oculi
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Humans
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Injections
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Macular Degeneration / complications
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Macular Degeneration / drug therapy
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Male
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Middle Aged
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Pigment Epithelium of Eye / drug effects
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Pigment Epithelium of Eye / pathology*
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Retinal Detachment / drug therapy
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Retinal Detachment / etiology
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Retinal Perforations / chemically induced*
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Retinal Perforations / diagnosis
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Tomography, Optical Coherence
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Vascular Endothelial Growth Factor A
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Vitreous Body
Substances
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Angiogenesis Inhibitors
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Antibodies, Monoclonal
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Antibodies, Monoclonal, Humanized
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Vascular Endothelial Growth Factor A
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Bevacizumab