Intacs for keratoconus and post-LASIK ectasia: mechanical versus femtosecond laser-assisted channel creation

Cornea. 2007 Sep;26(8):956-62. doi: 10.1097/ICO.0b013e31811dfa66.

Abstract

Purpose: To evaluate the efficacy of intracorneal ring segments to treat keratoconus and post-laser in situ keratomileusis (LASIK) keratectasia implanted by using either mechanical dissection or a femtosecond laser.

Methods: Thirty-three eyes of 29 patients had intracorneal ring segments implanted by using mechanical dissection (17 eyes) or a femtosecond laser (16 eyes). Mean follow-up was 10.3 months. Parameters assessed before and after surgery included uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), manifest refractive spherical equivalent (MRSE), refractive cylinder (RC), best contact lens-corrected visual acuity (BCLVA), and contact lens tolerance.

Results: Statistically significant changes occurred for all parameters when we analyzed all 33 eyes as 1 group. Mean UCVA LogMar values improved from 1.0 +/- 0.3 (20/200) to 0.6 +/- 0.4 (20/80) (P < 0.0005). Mean BSCVA changed from 0.3 +/- 0.2 (20/40) to 0.2 +/- 0.2 (20/30) (10%; P < 0.05), and MRSE from -9 +/- 4 to -7 +/- 4 D (P < 0.05; 20%). There was a decrease of 0.5 D or more of RC in 62% of eyes. BCLVA improved from 0.2 +/- 0.2 (20/30) to 0.1 +/- 0.1 (20/25) after surgery (P < 0.02). Contact lens tolerance improved in 81% of eyes. There was no statistically significant difference in outcomes between mechanical dissection and femtosecond laser-assisted techniques. However, although statistical power was adequate to detect changes in clinical parameters as a result of surgery, it was not sufficient to conclusively show such differences between surgical techniques.

Conclusions: For mild to moderate cases of keratoconus and post-LASIK keratectasia, the use of a femtosecond laser for Intacs channel creation seems as effective as mechanical dissection. Future studies are warranted to further evaluate channel creation by a femtosecond laser.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Corneal Stroma / physiopathology
  • Corneal Stroma / surgery*
  • Dilatation, Pathologic / etiology
  • Dilatation, Pathologic / surgery
  • Female
  • Follow-Up Studies
  • Humans
  • Intraoperative Complications
  • Keratoconus / physiopathology
  • Keratoconus / surgery*
  • Keratomileusis, Laser In Situ / adverse effects*
  • Male
  • Middle Aged
  • Polymethyl Methacrylate
  • Postoperative Complications
  • Prostheses and Implants*
  • Prosthesis Implantation / methods*
  • Refraction, Ocular / physiology
  • Retrospective Studies
  • Visual Acuity / physiology

Substances

  • Polymethyl Methacrylate