Abstract
We describe a case of traumatic endophthalmitis due to Scedosporium apiospermum that was successfully treated with a combination of intravitreal and systemic voriconazole. A high dose of 200 microg was used intravitreally without any apparent complications. A brief overview of voriconazole use for treatment of ocular infections is presented, and a comparison is made with antifungal agents traditionally used in ophathalmology.
MeSH terms
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Antifungal Agents / therapeutic use*
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Child
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Endophthalmitis / diagnosis
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Endophthalmitis / drug therapy
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Endophthalmitis / microbiology*
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Eye Infections, Fungal / diagnosis
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Eye Infections, Fungal / drug therapy
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Eye Infections, Fungal / microbiology*
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Eye Injuries, Penetrating / diagnosis
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Eye Injuries, Penetrating / drug therapy
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Eye Injuries, Penetrating / microbiology*
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Female
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Humans
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Injections
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Mycetoma / diagnosis
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Mycetoma / drug therapy
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Mycetoma / microbiology*
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Pyrimidines / therapeutic use*
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Scedosporium / isolation & purification*
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Triazoles / therapeutic use*
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Vitreous Body
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Voriconazole
Substances
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Antifungal Agents
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Pyrimidines
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Triazoles
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Voriconazole