Use of whole-body FDG PET-CT to aid in the diagnosis of occult sarcoidosis

Ocul Immunol Inflamm. 2008 Jan-Feb;16(1):25-7. doi: 10.1080/09273940801899798.

Abstract

Purpose: To report a case where combined whole-body Fluorine-18 fluorodeoxyglucose (FDG) PET-CT scanning was used to aid in the diagnosis of a patient with occult sarcoidosis.

Design: Case report.

Methods: FDG PET-CT scanning was performed in a patient who presented with persistent bilateral panuveitis after cataract surgery and had undergone an extensive negative workup.

Results: FDG PET-CT scanning demonstrated extensive mediastinal adenopathy. Biopsy showed a non-caseating granuloma with associated giant cell formation consistent with a diagnosis of sarcoidosis.

Conclusions: FDG PET-CT scanning generates tomographic scans with excellent sensitivity, spatial resolution, and anatomical landmark identification and may be useful in the workup of idiopathic uveitis.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Cataract Extraction
  • Female
  • Fluorodeoxyglucose F18*
  • Humans
  • Positron-Emission Tomography*
  • Postoperative Complications / etiology
  • Radiopharmaceuticals*
  • Sarcoidosis / complications
  • Sarcoidosis / diagnosis*
  • Tomography, X-Ray Computed*
  • Uveitis / etiology

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18