Structure of Lisch nodules in neurofibromatosis type 1

Ophthalmic Paediatr Genet. 1991 Mar;12(1):11-7. doi: 10.3109/13816819109023079.

Abstract

Postmortem examination of the eyes of a patient with neurofibromatosis Type I was performed by light and electronmicroscopy. Lisch nodules were examined and found to consist of a condensation of spindle cells on the anterior iris surface. When nodules were pigmented an underlying stromal naevus was present. Lisch nodules are confirmed as being of melanocytic origin.

Publication types

  • Case Reports

MeSH terms

  • Humans
  • Infant
  • Iris / ultrastructure*
  • Iris Neoplasms / ultrastructure*
  • Male
  • Neurofibromatosis 1 / pathology*
  • Nevus, Pigmented / ultrastructure*