Purpose: To identify factors related to non-penetrating deep sclerectomy (NPDS) failure in controlling intraocular pressure (IOP).
Methods: A case-control study was performed through a logistic regression modelling. All cases and controls had at least 2 years of follow-up. Cases comprised eyes that had undergone an NPDS and presented an end-point IOP > 18 mmHg; controls consisted of eyes that had undergone an NPDS and achieved an end-point IOP < 18 mmHg without medication. Cases and controls were paired by sex and postoperative time. The following independent variables were tested: race, previous ocular surgery, number of topical medications prior to surgery, age, preoperative IOP, severity of glaucomatous visual field loss, use of mitomycin C (MMC), YAG laser goniopuncture and IOP in the first day after surgery.
Results: Two hundred and sixty-nine eyes were studied (136 cases and 133 controls). Absence of intraoperative MMC and high preoperative IOP were related to an end-point IOP > 18 mmHg after 2 years of follow-up.
Conclusion: Two factors seem to be associated to NPDS failure: the absence of intraoperative MMC and preoperative IOP.
© 2009 The Authors. Journal compilation © 2009 Acta Ophthalmol.