Abstract
Purpose:
A 2-year-old boy with syndromic bilateral retinoblastoma resulting from a (del(13)(q12.3q14.3)) developed a recurrent tumor measuring 2.3 X 2.3 mm at the ora serrata 15 months following last treatment.
Methods:
Ultrasound biomicroscopy (UBM) revealed a mass invading the ciliary body 6.6 mm in diameter associated with a localized supraciliary effusion.
Results:
Complete tumor regression was achieved 1 month after brachytherapy with a (106)Ruthenium plaque. There was no recurrence at 16 months.
Conclusion:
This is the first clinical demonstration of supraciliary effusion in recurrent retinoblastoma. Brachytherapy appears to be effective in the treatment of this type of recurrence.
MeSH terms
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Brachytherapy*
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Child, Preschool
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Chromosome Deletion
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Chromosomes, Human, Pair 13 / genetics
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Ciliary Body / diagnostic imaging
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Ciliary Body / pathology
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Ciliary Body / radiation effects*
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Humans
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Male
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Microscopy, Acoustic
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Neoplasm Invasiveness
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Neoplasm Recurrence, Local / diagnostic imaging
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Neoplasm Recurrence, Local / pathology
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Neoplasm Recurrence, Local / radiotherapy*
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Retinal Neoplasms / diagnostic imaging
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Retinal Neoplasms / genetics
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Retinal Neoplasms / radiotherapy*
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Retinoblastoma / diagnostic imaging
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Retinoblastoma / genetics
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Retinoblastoma / radiotherapy*
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Ruthenium Radioisotopes / therapeutic use*
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Uveal Neoplasms / diagnostic imaging
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Uveal Neoplasms / pathology
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Uveal Neoplasms / radiotherapy*